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Bristol Bears produced an outstanding display to overcome top-four contenders Gloucester 28-24 in the West Country derby at Ashton Gate.
Four games are set to take place in the Premiership on Saturday, while Newcastle v Worcester round off the action at Kingston Park on Sunday.
Sale Sharks have confirmed that Rob Webber has extended his contract by a further 12 months, taking him to the end of the 2020/21 campaign.
Luke Morahan returns from injury to start in a highly anticipated West Country derby between Bristol Bears and Gloucester at Ashton Gate.
Worcester have announced that Bryce Heem has opted to pursue his career outside of the Premiership after four seasons playing in England.
Saracens have confirmed that Schalk Burger will leave the club at the end of the season, ending a three-year association with the Londoners.
Former England international centre and Leicester stalwart Mathew Tait has announced his retirement following 15 years in professional rugby.