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England and Saracens number eight Billy Vunipola has been ruled out for 12 weeks after suffering a broken arm against Glasgow on Sunday.
With the dust having settled on Round One of the Champions Cup, we have gone through the action to pick the best players from the games.
Saracens got their Champions Cup campaign off to a winning start with a 13-3 victory over Glasgow Warriors at Scotstoun on Sunday.
Four fixtures take place on Sunday in Round One of the Champions Cup, starting with Gloucester hosting Castres and Lyon facing Cardiff Blues.
With the 2018/19 European Champions Cup kicking off this weekend, we give our verdict on which teams will be in the hunt for the trophy.
Check out highlights from Round Six of Premiership action.
Following victories from Gloucester, Leicester Tigers and Sale Sharks earlier in the day, Saracens came from behind to overcome Harlequins.