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Northampton set up a tantalising decider with Munster with a bonus-point 34-0 win over Perpignan at Franklin's Gardens on Sunday.
London Irish's hopes of making the Heineken Cup quarter-finals were dealt a mortal blow on Sunday as they fell 31-22 to the Scarlets.
A Brian O'Driscoll try in the final minute handed Lienster a bonus-point 27-10 win over Brive in the Heineken Cup on Saturday.
Clermont weathered an early storm from the Ospreys to win 27-7 and assume a commanding position in the Heineken Cup Pool Three.
Cardiff Blues gave their Heineken Cup hopes a huge shot in the arm with a 36-19 win that also starved Sale a losing bonus point.
Gloucester kept their faint hopes of making the Heineken Cup last eight alive after recording a 23-8 win over Biarritz on Saturday.
Stade FranÃ§ais returned to the summit of Pool 4 on Saturday thanks to a highly scrappy 15-13 victory over Bath at Stade Jean Bouin.
Leicester moved temporarily top of Pool 3 on Saturday thanks to an emphatic 47-8 victory over Viadana at Welford Road.
Munster are in pole position to finish top of Pool One in the Heineken Cup after their 44-7 thrashing of Treviso on Saturday.
Ulster moved level on points with Stade FranÃ§ais at the Pool 4 summit on Friday thanks to a 21-13 victory over Edinburgh.
Glasgow moved off the bottom of Pool 2 on Friday with an entertaining 29-25 Heineken Cup victory over the Dragons at Firhill.
Ulster have named their side that will run out to face old rivals in a vital Heineken Cup fixture at Ravenhill this Friday.
Munster coach Tony McGahan has named a side along the expected lines for Saturday's clash with Treviso at the Stadio Comunale di Monigo.
Biarritz can confirm their place in the quarter-finals with a Pool Two victory at struggling Gloucester on Saturday.
Leicester welcome back local hero Sam Vesty for his first start of the season in Saturday's Heineken Cup tie against Viadana.
Clermont have named a frighteningly strong XV to take on the Ospreys for what is arguably the biggest game of Round Five.
Harlequins will send their first choice XV to Toulouse on Sunday for their Heineken Cup clash at Stade Ernest Wallon.
Pool 4 pace-setters Stade FranÃ§ais will be hoping to all-but seal their progression into the Heineken Cup knockout stages against Bath.
Heineken Cup holders Leinster will be craving a bonus-point victory over basement side Brive at the RDS on Saturday.
Five London Irish players in the England and Saxons squad are included in the team for Sunday's Heineken Cup match with Scarlets.