Pat Lambie will captain a Springbok team containing six uncapped players for their match against the Barbarians at Wembley on Saturday.
The matchday 23 for the Springboks’ first of four November matches includes a total of nine uncapped players, however, no Test caps will be awarded for this international fixture.
The newcomers in the starting line-up are RG Snyman (lock), Roelof Smit (flank), Jamba Ulengo (wing), Rohan Janse van Rensburg (inside centre), Francois Venter (outside centre) and Sergeal Petersen (wing).
Tendai Mtawarira (prop), Pieter-Steph du Toit (lock) and Oupa Mohoje (flank) are the only players in the pack that started for the Springboks against the All Blacks in Durban last month.
There is a return to the starting team for Lourens Adriaanse in the number three jersey in place of Vincent Koch who is not available for this match, while Julian Redelinghuys is injured. Snyman will partner Du Toit, the newly-crowned SA Rugby Player of the Year, in the second-row.
Openside flanker Smit comes in for the injured Francois Louw, while Jaco Kriel could also not be considered as a result of his injury. The final change in the pack will see Nizaam Carr taking over the number eight jersey from Warren Whiteley who is also not available for this match.
The Boks will start with a revamped half-back pairing in Rudy Paige (scrum-half) and new skipper Lambie (fly-half), with regular captain, Adriaan Strauss, not in the match 23 as part of the succession planning in his position.
The rest of the backline consists of Ulengo, Janse van Rensburg, Venter, Petersen and Jesse Kriel, who will start his first match for the Boks at full-back.
Springbok coach Allister Coetzee said the Springboks’ aim was to improve after a difficult season, but that it would not be easy against the Barbarians.
"The Barbarians play an attacking, adventurous style of rugby and it will be a real test for our young side," said Coetzee.
"They have an excellent, world-renowned coach in Robbie Deans, exciting young players in their side, including some South Africans, as well as several players who have a lot of Test match experience.
"We rewarded several young players for their performances in Super Rugby and the Currie Cup and we will approach this match as a Test, although no caps will be awarded.
"It will be a really big occasion for our young players, but we’re excited to be giving them an opportunity. Even though some of the experienced players were last in action against New Zealand four weeks ago, our preparation the past few weeks was really good.
"The excitement and enthusiasm of the new inclusions is contagious. In ideal circumstances I would’ve preferred to give every player in the squad a run, but this tour was also about introducing players who are on our radar for the future, while also introducing them to the Springbok way and ethos. I am sure they will work even harder to stay in the squad."
South Africa: 15 Jesse Kriel, 14 Sergeal Petersen, 13 Francois Venter, 12 Ruan Janse van Rensburg, 11 Jamba Ulengo, 10 Patrick Lambie (c), 9 Rudy Paige, 8 Nizaam Carr, 7 Teboho Mohoje, 6 Roelof Smith, 5 Pieter-Steph du Toit, 4 Rudolf Snyman, 3 Lourens Adriaanse, 2 Malcolm Marx, 1 Tendai Mtawarira
Replacements: 16 Bongi Mbonambi, 17 Lizo Gqoboka, 18 Trevor Nyakane, 19 Eben Etzebeth, 20 Jean-Luc du Preez, 21 Piet van Zyl, 22 Tiaan Schoeman, 23 Ruan Combrinck
Date: Saturday, November 5
Venue: Wembley Stadium, London
Kick-off: 15:00 local
Referee: Mike Fraser (New Zealand)
Assistant Referees: Paul Williams (New Zealand), Shuhei Kubo (Japan)
TMO: Graham Hughes (England)