He is joined in the front-row by Cian Healy and Tadhg Furlong. Iain Henderson and James Ryan start at lock with Peter O’Mahony, Sean O’Brien and CJ Stander filling the back-row slots.
Kieran Marmion partners Jonathan Sexton at half-back with Bundee Aki and Robbie Henshaw at inside and outside centre respectively.
Jordan Larmour is named at full-back for his first start at Aviva Stadium. He is joined in the back three by Jacob Stockdale and Keith Earls.
The replacements for Saturday are Sean Cronin, Jack McGrath, Andrew Porter, Devin Toner, Dan Leavy, Luke McGrath, Joey Carbery and Andrew Conway.
Ireland: 15 Jordan Larmour, 14 Keith Earls, 13 Robbie Henshaw, 12 Bundee Aki, 11 Jacob Stockdale, 10 Jonathan Sexton, 9 Kieran Marmion, 8 CJ Stander, 7 Sean O’Brien, 6 Peter O’Mahony, 5 James Ryan, 4 Iain Henderson, 3 Tadhg Furlong, 2 Rory Best (c), 1 Cian Healy
Replacements: 16 Sean Cronin, 17 Jack McGrath, 18 Andrew Porter, 19 Devin Toner, 20 Dan Leavy, 21 Luke McGrath, 22 Joey Carbery, 23 Andrew Conway
Date: Saturday, November 10
Venue: Aviva Stadium
Kick-off: 18:30 GMT
Referee: Nic Berry (Australia)
Assistant referees: Angus Gardner (Australia), Ludovic Cayre (France)
Television match official: David Grashoff (England)