England have named Brad Shields on the blindside flank for their second Test against South Africa at the Free State Stadium on Saturday.
There are two changes to the starting XV that played on Saturday with Shields making his first England start at six and Joe Launchbury coming in for Nick Isiekwe, having recovered from his calf injury.
Cipriani is named as a replacement ahead of Piers Francis on the bench. Cipriani’s last cap for England came against France ahead of the Rugby World Cup in 2015.
“We have come here to win the series against South Africa and the squad is ready to go out and beat them this weekend,” said head coach Eddie Jones.
“We have had a very good preparation this week and the intensity and executions in those sessions are going to put us in a good position for Saturday.”
England lost the first match of the three-Test series against South Africa in Johannesburg 42-39 on Saturday. Their final match is in Cape Town (23 June).
Owen Farrell will captain the side at 12, again joining Henry Slade in midfield, with Ben Youngs and George Ford England’s half-back pairing.
Launchbury partners Maro Itoje in the second-row, while flankers Tom Curry and Shields join Billy Vunipola in the back-row.
Elliot Daly is named at full-back again with Mike Brown and Jonny May on the wings.
England: 15 Elliot Daly, 14 Jonny May, 13 Henry Slade, 12 Owen Farrell (c), 11 Mike Brown, 10 George Ford, 9 Ben Youngs, 8 Billy Vunipola, 7 Tom Curry, 6 Brad Shields, 5 Maro Itoje, 4 Joe Launchbury, 3 Kyle Sinckler, 2 Jamie George, 1 Mako Vunipola
Replacements: 16 Luke Cowan-Dickie, 17 Joe Marler, 18 Harry Williams, 19 Mark Wilson, 20 Nathan Hughes, 21 Ben Spencer, 22 Danny Cipriani, 23 Denny Solomona
Date: Saturday, June 16
Venue: Free State Stadium, Bloemfontein
Kick-off: 17:05 local (16:05 BST, 15:05 GMT)
Referee: Romain Poite (France)
Assistant referees: Glen Jackson (New Zealand), Ben O’Keeffe (New Zealand)
Television match official: Simon McDowell (Ireland)