Joe Cokanasiga and Jamie George retain England places
England head coach Eddie Jones has kept faith with wing Joe Cokanasiga and hooker Jamie George for the game against Australia at Twickenham on Saturday.
Cokanasiga starts after fellow back three players Jack Nowell and Chris Ashton were ruled out, while George is preferred to co-captain Dylan Hartley.
Manu Tuilagi returns to the 23 after being forced to pull out before the opening November Test encounter versus South Africa and is joined on the bench by Nathan Hughes.
Elsewhere, there are several changes from the Japan contest with the majority of the team that ran New Zealand close being selected.
Henry Slade and Ben Te’o start at centre while Owen Farrell and Ben Youngs combine at half-back.
In the pack, Ben Moon and Kyle Sinckler join George in the front-row, with Courtney Lawes packing down behind the trio after shifting from the blindside.
The back-row once again sees Brad Shields, Sam Underhill and Mark Wilson lining up together after impressing against the All Blacks.
“We’ve picked our best 23 for the Australia game,” said Jones. “We know they have a unique style of attack so our ability to defend that is going to be important.
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“We are continually working on our strengths which is our set piece and our defence and they are areas that are progressing nicely.
“Australia, we know are a traditional rival and we enjoy the occasion of playing them at Twickenham. The spirit of the fans has been outstanding.
“I think the atmosphere during these Quilter Internationals has been the best atmosphere I’ve certainly experienced and we encourage the fans to be at their robust best at the weekend.”
England: 15 Elliot Daly, 14 Joe Cokanasiga, 13 Henry Slade, 12 Ben Te’o, 11 Jonny May, 10 Owen Farrell (c), 9 Ben Youngs, 8 Mark Wilson, 7 Sam Underhill, 6 Brad Shields, 5 Courtney Lawes, 4 Maro Itoje, 3 Kyle Sinckler, 2 Jamie George, 1 Ben Moon
Replacements: 16 Dylan Hartley, 17 Alec Hepburn, 18 Harry Williams, 19 Charlie Ewels, 20 Nathan Hughes, 21 Richard Wigglesworth, 22 George Ford, 23 Manu Tuilagi
Date: Saturday, November 24
Venue: Twickenham, London
Kick-off: 15:00 GMT
Referee: Jaco Peyper (South Africa)
Assistant Referees: Glen Jackson (New Zealand), Alexandre Ruiz (France)
TMO: Marius Jonker (South Africa)