The Scarlets claimed bragging rights in their derby against Cardiff as they sealed a 29-23 win while the Lions clinched a 49-24 victory over the Dragons.
Wales and the Scarlets suffered a blow after fly-half Sam Costelow was injured during his country's match against the Barbarians in Cardiff on Saturday.
Check on the team news and our predictions for Round Three of the United Rugby Championship, with two games on Friday, five on Saturday and one more on Sunday.
The Stormers handed the Scarlets their second successive heavy URC loss while Connact and the Ospreys sealed wins over Glasgow Warriors and Zebre Parma respectively.