Toulon claimed a 34-12 success over Agen at Felix-Mayol on Tuesday, which moves them above their visitors and into third position in the Top 14 table.
In his first game since announcing his retirement from Test rugby, Jonny Wilkinson sent over four penalties but missed with his three conversions, the first being as early as the second minute following centre Gabiriele Lovobalavu's crossing.
Conrad Barnard did reduce the scoreline to 5-3 minutes later but then followed three Wilkinson efforts that took hosts RC Toulon 14-3 up in this rearranged fixture, which had been affected by an outbreak of parotiditis, a salivary gland infection.
Barnard was again successful from the tee but then Toulon number eight Jone Tawake went in for what looked like being a decisive try in the game, with Wilkinson's conversion to come. However, the Englishman missed the kick and that led to Barnard sending the teams in at 19-9.
Upon the turnaround, Toulon were soon going over for their third try when flanker Leonardo Senatore crossed, but again Wilkinson missed and Barnard made him pay with three more.
But that was the last offering from the visiting fly-half as Toulon eventually scored a fourth following Wilkinson's penalty on 54 minutes, with replacement Konstantin Mikautadze going over. Matt Giteau kicked the conversion that sends Toulon eight points behind Toulouse.
Tries: Lovobalavu, Tawake, Senatore, Mikautadze
Pen: Wilkinson 4
Pen: Barnard 4
RC Toulon: 15 Luke Rooney, 14 Alexis Palisson, 13 Gabiriele Lovobalavu, 12 Matt Giteau, 11 David Smith, 10 Jonny Wilkinson, 9 Sebastien Tillous-Borde, 8 Jone Tawake, 7 Steffon Armitage, 6 Leonardo Senatore, 5 Dean Schofield, 4 Kris Chesney, 3 Davit Kubriashvili, 2 Sebastien Bruno, 1 Laurent Emmanuelli.
Replacements:16 Jean Philippe Genevois, 17 Eifion Lewis Roberts, 18 Konstantin Mikautadze, 19 Pierrick Gunther, 20 Mathieu Bastareaud, 21 Benjamin Lapeyre, 22 Matt Henjak, 23 Carl Hayman.
SU Agen: 15 Silvere Tian, 14 Saimoni Vaka, 13 Senio Junior Pelesasa, 12 Jamie Robinson, 11 Brice Dulin, 10 Conrad Barnard, 9 Maxime Machenaud, 8 Ueleni Fono, 7 Adriaan Badenhorst (c), 6 Jean Monribot, 5 Lisiate Faaoso, 4 Dewald Senekal, 3 Gert Muller, 2 Jalil Narjissi, 1 John Schwalger.
Replacements: 16 Julien Janaudy, 17 Laurent Cabarry, 18 Patrick O'Connor, 19 Damien Lagrange, 20 Alexi Bales, 21 Manu Ahotaeiloa, 22 Miguel Avramovic, 23 Martin Scelzo.
Referee: Laurent Cardona