Clermont made light work of Leicester in their Heineken Cup clash, winning 30-12 at Stade Marcel Michelin on Sunday.
Two Wesley Fofana tries damaged the Tigers' hopes of qualifying from Pool 4 in the first of back-to-back enounters between the two sides.
The 49th-minute double sin-binning of England centre Manu Tuilagi and hooker George Chuter, when 16-5 down, proved deicisive as the thirteen Tigers could not prevent Fofana from scoring soon after.
That converted score gave the hosts a virtually unassailable 23-5 lead with less than half an hour remaining. And when Clermont's inside centre struck again with 14 minutes left the game was up for the visitors.
Clermont took an early lead courtesy of a Morgan Parra penalty, after Leicester had infringed at the line-out. The Tigers hit back though and had the lead when Ben Youngs crossed for a try after Toby Flood's long-range kick had got the visitors into a good position.
Flood missed the conversion, however, and a second Parra penalty gave the hosts a narrow advantage with a quarter of the game played. 6-5 became 9-5 ten minutes later when Parra struck again after Leicester's Tom Croft was penalised for putting his hands in the ruck.
Clermont then crossed for a pivotal try minutes before the interval, Parra finding Julien Malzieu with a peach of a pass, before converting to make it 14-5.
Disaster struck for Leicester nine minutes into the second half when Manu Tuilagi and Chuter were both dispatched to the sin-bin for reckless tackles. Clermont capitalised on the numerical advantage and extended their lead thanks to a try from Wesley Fofana after Malzieu had made the initial break.
Leicester were back to full numbers on the hour, but saw the game slip away from them minutes later when Fofana grabbed his second when he pounded on a Brock James kick.
Parra's conversions made it 30-5 but, following the sin-binning of Clermont's Julien Bonnaire, Leicester were able to salvage some pride in the closing stages with a penalty try awarded following a scrum.
Tries: Fofana 2, Malzieu
Cons: Parra 3
Pens: Parra 3
For Leicester Tigers:
Tries: Youngs, Penalty Try
ASM Clermont Auvergne:15 Lee Byrne, 14 Sitiveni Sivivatu, 13 Aurélien Rougerie, 12 Wesley Fofana, 11 Julien Malzieu, 10 Brock James, 9 Morgan Parra, 8 Julien Bonnaire, 7 Alexandre Lapandry, 6 Gerhard Vosloo, 5 Nathan Hines, 4 Julien Pierre, 3 Davit Zirakashvili, 2 Benjamin Kayser, 1 Lionel Faure.
Replacements: 16 Ti'i Paulo, 17 Vincent Debaty, 18 Clément Ric, 19 Jamie Cudmore, 20 Elvis Vermeulen, 21 Kevin Senio, 22 David Skrela, 23 Regan King.
Leicester Tigers: 15 Geordan Murphy, 14 Horacio Agulla, 13 Matt Smith, 12 Manu Tuilagi, 11 Alesana Tuilagi, 10 Toby Flood, 9 Ben Youngs, 8 Thomas Waldrom, 7 Jules Salvi, 6 Tom Croft, 5 George Skivington, 4 Louis Deacon, 3 Martin Castrogiovanni, 2 George Chuter, 1 Marcos Ayerza.
Replacements: 16 Rob Hawkins, 17 Boris Stankovich, 18 Dan Cole, 19 Ed Slater, 20 Steve Mafi, 21 Sam Harrison, 22 Billy Twelvetrees, 23 Scott Hamilton,
Referee: Alain Rolland (Ireland)