Matt Mullan will make his first start for Worcester Warriors since October when the club entertains Olympus Rugby XV Madrid at Sixways on Saturday.
Prop Mullan, who was this week named in the England Saxons EPS squad, will join skipper Chris Fortey and Olivier Sourgens in the front row for the Round five clash in Pool Two.
French ace Sourgens and lock Craig Gillies are the only survivors from the side that drew with Gloucester Rugby in the Guinness Premiership.
Graham Kitchener, James Collins, Jake Abbott and Matt Cox are all named in the pack as director of rugby Mike Ruddock selects a side with a mix of youth and experience.
Ryan Powell and Matthew Jones are paired at half back and Marcel Garvey returns on the wing.
Scotland international Alex Grove and Sam Tuitupou combine in the centre will Calum MacRae completing an exciting back division.
Fit again duo David Lyons and Joe Carlisle are named among the replacements.
Worcester: 15 Calum MacRae, 14 Marcel Garvey, 13 Alex Grove, 12 Sam Tuitupou, 11 Chris Pennell, 10 Matthew Jones, 9 Ryan Powell, 8 Matt Cox, 7 Jake Abbott, 6 James Collins, 5 Craig Gillies, 4 Graham Kitchener, 3 Olivier Sourgens, 2 Chris Fortey (c), 1 Matt Mullan.
Replacements: 16 Adam Black, 17 Aleki Lutui, 18 Jack Gilding, 19 David Lyons, 20 Kai Horstmann, 21 Ollie Frost, 22 Joe Carlisle, 23 Greg King.
Olympus Madrid: 15 Matias Tudela, 14 Juan Cano, 13 Martin Heredia, 12 Jeremias Palumbo, 11 Benjamin Pardo, 10 Cesar Sempere, 9 Pablo Feijoo, 8 Matthew Cook, 7 Gensen Palmers, 6 Rafael Camacho, 5 Jesus Recuerda, 4 Sergio Souto, 3 David Gurgenazde, 2 Chema Bohorquez, 1 Alejandro Onega Camacho.
Replacements: 16 Javier Arbelaitz, 17 Manuel Serrano, 18 Sebastian Hattori, 19 Leandro Fernandez, 20 Ivan Criado, 21 Martin Acena, 22 Javier Canosa, 23 Carlos Arenas.
Date: Saturday, January 16
Kick-off: 15.00 GMT
Referee: Leighton Hodges (Wales)