Two play-off contenders will go toe-to-toe as Round 14 of the Top 14 begins with a clash between Stade Franšais and Grenoble at Stade Jean Bouin.
One of these sides will move up to second spot in the standings on Friday ahead of Saturday's busy schedule, with the Paris side favourites to win.
Stade Franšais bounced back from a Challenge Cup loss at London Irish a fortnight ago with a home win over the Premiership side last week.
Grenoble meanwhile enter the game on the back of successive defeats to Wasps and will be keen to return to winning ways, particularly as they are just three points off the dream that is the top four.
Friday's travelling side admitted they viewed the Challenge Cup as a chance to rest players so they will be raring to shine after going into the break on the back of a narrow loss at Bayonne.
Stade Franšais: 15 Hugo Bonneval, 14 Julien Arias, 13 Geoffrey Doumayrou, 12 Meyer Bosman, 11 Djibril Camara, 10 Morne Steyn, 9 Julien Dupuy, 8 Sergio Parisse (c), 7 Pierre Rabadan, 6 Antoine Burban, 5 Pascal Pape, 4 Alexandre Flanquart, 3 Rabah Slimani, 2 Laurent Sempere, 1 Heinke van der Merwe.
Replacements: 16 Michael van Vuuren, 17 Sakaria Taulafo, 18 Gerhard Mostert, 19 David Lyons, 20 Jerome Fillol, 21 Jules Plisson, 22 Paul Williams, 23 Davit Kubriashvili.
Grenoble: 15 Fabien Gengenbacher, 14 Alipati Ratini, 13 Rida Jaouher, 12 Geoffroy Messina, 11 Julien Caminati, 10 Blair Stewart, 9 James Hart, 8 Peter Kimlin, 7 Fabien Alexandre, 6 Jonathan Best, 5 Hendrik Roodt, 4 Ben Hand, 3 Dayna Edwards, 2 Anthony Hegarty, 1 Albertus Buckle.
Replacements: 16 Kenan Mutapcic, 17 Vincent Campo, 18 Naude Beukes, 19 Florian Faure, 20 Benjamin Thiery, 21 Rudi Coetzee, 22 Nicolas Bezy, 23 Richard Choirat.
Result last season: Stade Franšais 35-6 Grenoble; Grenoble 26-12 Stade Franšais
Prediction: TBC once both teams announced
Kick-off: 20:45 local (19:45 GMT)
Referee: Christophe Berdos
Assistant referees: Eric Soulan, Pascal Ubeda
Television match official: Jean-Claude Levrier