Round Six of the Top 14 kicks-off at Stade Aimé Giral on Friday when an in-form Montpellier travel to Perpignan in what should be a fascinating clash.
Montpol enter on the back of a 25-0 victory over Toulouse while USAP narrowly lost out to Racing Metro 19-16 in Paris in a result that will sting.
The hosts must recover though and do it without Richard Haughton, Tommaso Benvenuti and Alasdair Strokosch, who aren't named in their 23.
Former Munster back Lifeimi Mafi is in the squad, as is Dewaldt Duvenage and Sona Taumalolo, after they missed out for Perpignan at Racing.
Perpignan currently sit in tenth position after two wins from five games while Montpellier are second, just one point behind leaders Toulon.
Meanwhile, Montpellier have made eight changes for this fixture as Anthony Floch, Yoan Audrin and Fulgence Ouedraogo do not feature in the 23.
Dropping to bench duty are Anthony Tuitavaké, Timoci Nagusa and Jonathan Pélissié, with Benoit Paillaugue joining key player Francois Trinh-Duc as the half-back combination.
Perpignan: 15 James Hook , 14 Wandile Mjekevu, 13 Lifeimi Mafi, 12 Sione Piukala, 11 Sofiane Guitoune, 10 Camille Lopez, 9 Dewaldt Duvenage, 8 Luke Narraway, 7 Jean pierre Perez, 6 Justin Purll, 5 Romain Taofifenua, 4 Sebastien Vahaamahina, 3 Giorge Jgenti, 2 Guilhem Guirado, 1 Sona Taumalolo.
Replacements: 16 Romain Terrain, 17 Sebastien Taofifenua, 18 Daniel Leo, 19 Karl Chateau, 20 Nicolas Durand, 21 David Marty, 22 Joffrey Michel, 23 Paulica Ion.
Montpellier: 15 Benoit Sicart, 14 Lucas Dupont, 13 Thomas Combezou, 12 Wynand Olivier, 11 Yohann Artru, 10 Francois Trinh-Duc, 9 Benoit Paillaugue, 8 Johnnie Beattie, 7 Alexandre Bias (capt), 6 Alex Tulou, 5 Thibaut Privat, 4 Robins Tchale-Watchou, 3 Nicolas Mas, 2 Charles Géli, 1 Yvan Watremez.
Replacements: 16 Mickael Ivaldi, 17 Na'ama Leleimalefaga, 18 Mickael De Marco, 19 Kélian Galletier, 20 Jonathan Pélissié, 21 Anthony Tuitavaké, 22 Timoci Nagusa, 23 Maximiliano Bustos.
Date: Friday, September 13
Kick-off: 18:45 local (17:45 BST)
Venue: Stade Aimé Giral
Referee: Christophe Berdos
Assistant referees: Tual Trainini, Thierry Laurent Grand
Television match official: Jean-Luc Pellaprat