Wales have named their side to face Australia at the Millennium Stadium, with wing Alex Cuthbert and fly-half Dan Biggar both starting on Saturday.
Cuthbert returns to the side after an ankle injury and takes the place of Hallam Amos on the right wing while Biggar comes in for James Hook.
Biggar gets the nod ahead of Rhys Priestland at ten after the duo and Perpignan's Hook enjoyed a start apiece in their previous three matches.
Scott Williams has recovered from a toe injury to be named in the midfield alongside Cardiff Blues centre Owen Williams, who scored on his first outing at the Millennium Stadium last Friday.
Gethin Jenkins, who became a centurion on his last outing for Wales a fortnight ago, returns with Richard Hibbard to the front-row. Rhodri Jones will start his third consecutive game at tighthead.
British and Irish Lions duo Ian Evans and Alun-Wyn Jones, who started all five of Wales' 2013 Six Nations games together, renew their partnership in the second-row.
The back-row will line up with Dan Lydiate at blindside, alongside captain Sam Warburton at openside and Toby Faletau at number eight.
"It's great to have Alex and Scott available and they bring a lot of experience into the backline," said head coach Warren Gatland.
"Alex and the medical teams have worked really hard to ensure he is ready for this weekend and it's great to be able to bring him back into the side.
"We thought Owen (Williams) performed well in the centre against Tonga and he gets another opportunity on Saturday.
"There is a lot of experience in the pack for what is going to be a very physical game. We are looking to finish the series off well, the last three games against Australia have gone right down to the wire and I don't expect anything different this weekend."
Wales: 15 Leigh Halfpenny, 14 Alex Cuthbert, 13 Owen Williams, 12 Scott Williams, 11 George North, 10 Dan Biggar, 9 Mike Phillips, 8 Toby Faletau, 7 Sam Warburton (capt), 6 Dan Lydiate, 5 Ian Evans, 4 Alun-Wyn Jones, 3 Rhodri Jones, 2 Richard Hibbard, 1 Gethin Jenkins.
Replacements: 16 Ken Owens, 17 Ryan Bevington, 18 Samson Lee, 19 Ryan Jones, 20 Justin Tipuric, 21 Rhodri Williams, 22 Rhys Priestland, 23 Liam Williams.
Date: Saturday, November 30
Kick-off: 17:00 GMT
Venue: Millennium Stadium
Referee: Wayne Barnes (England)
Assistant referees: Alain Rolland (Ireland), John Lacey (Ireland)
Television match official: Jim Yuille (Scotland)
Assessor: Clayton Thomas (Wales)