Scarlets centre Scott Williams has been ruled out of Wales' tour to Japan due to the recurrence of a shoulder injury.
Williams was included in Robin McBryde's training squad for the tour but along with team-mates Ken Owens and Liam Williams was being monitored by medical staff.
It has now been confirmed that Williams will take no part in the tour due to the injury and will return to Scarlets to continue his recovery.
No replacement will be named, with McBryde set to name his final 27-man squad on May 21.
Wales will face Japan in two Tests on on June 8 and 15.