Bath have handed the club captain's armband to second-row Dave Attwood for their Amlin Challenge Cup quarter-final match against Brive on Sunday.
Attwood is partnered by Dominic Day in the engine room, as Carl Fearns starts at number eight alongside Matt Garvey and Guy Mercer in their back-row. Loosehead prop Nathan Catt, last week's centurion, and tighthead Anthony Perenise are named on either side of Ross Batty at hooker.
Micky Young resumes his half-back partnership with George Ford, whilst there is a new midfield partnership of Gavin Henson and Matt Banahan.
Semesa Rokoduguni and Horacio Agulla provide the pace and power out wide on the wings, with Nick Abendanon continuing in the full-back shirt.
Brive meanwhile have made wholesale changes to the team that stunned Clermont in the Top 14 last week, with only second-row Julien Le Devedec keeping his place in the starting line-up.
There is no Gaetan Germain, Guillaume Namy, Arnaud Mignardi, Riaan Swanepoel, Sisaro Koyamaibole or Kevin Buys as Bath face a new-look side whose priorities seem elsewhere.
Bath: 15 Nick Abendanon, 14 Horacio Agulla, 13 Matt Banahan, 12 Gavin Henson, 11 Semesa Rokoduguni, 10 George Ford, 9 Micky Young, 8 Carl Fearns, 7 Guy Mercer, 6 Matt Garvey, 5 David Attwood (c), 4 Dominic Day, 3 Anthony Perenise, 2 Ross Batty, 1 Nathan Catt.
Replacements: 16 Tom Dunn, 17 Paul James, 18 David Wilson, 19 Stuart Hooper, 20 Leroy Houston, 21 Martin Roberts, 22 Kyle Eastmond, 23 Anthony Watson.
Brive: 15 Laurent Ferreres, 14 Venione Voretamaya, 13 Baptiste Delage, 12 Thomas Laranjeira, 11 Sevanaia Galala, 10 Romain Sola, 9 Thomas Sanchou (c), 8 Kieran Murphy, 7 Fabien Laurent, 6 Apisai Naikatini, 5 Simon Pinet, 4 Julien Le Devedec, 3 Johannes Coetzee, 2 Louis Acosta, 1 Damien Lavergne.
Replacements: 16 Goderzi Shvelidze, 17 Tamato Leupolu, 18 Yusuf Tuncer, 19 Victor Lebas, 20 Hugues Briatte, 21 Romain Kusiolek, 22 Andrew Mailei, 23 Anderson Neisen.
Date: Sunday, April 6
Kick-off: 14:00 BST
Venue: Recreation Ground
Referee: John Lacey (Ireland)
Assistant referees: Dudley Phillips (Ireland), Sean Gallagher (Ireland)
TMO: Jim Yuille (Scotland)