Treviso enter their PRO12 fixture against Munster at Thomond Park full of confidence after beating reigning champions the Ospreys last week.
The impressive 12-6 win over the Welsh region in poor weather conditions caused a stir in Round One, and they face another tough game on Friday.
Brendan Williams has been named at full-back in place of Kristopher Burton, who drops to bench duty, while Luca Morisi comes in at centre, which leads to Luke McLean dropping out of the 22.
Up front, Michele Rizzo and Lorenzo Cittadini are preferred over Alberto De Marchi and Lorenzo Cittadini as props, Valerio Bernab˛ and Antonio Pavanello come in at lock while Paul Derbyshire and Dean Budd earn a run in the back-row.
Munster coach Rob Penney has made two changes following their opening round win in Edinburgh.
Those changes occur up front with Stephen Archer getting in on this ocasion ahead of BJ Botha at prop while Dave O'Callaghan gets the nod over Paddy Butler at number six.
Form: Munster began their 2012/13 RaboDirect PRO12 campaign with a 23-18 victory against Edinburgh at Murrayfield. The Munstermen have won seven of their last eight home games in the competition. Munster lost their most recent encounter with an Italian opponent: 17-21 at Aironi in March. Benetton Treviso beat Ospreys 12-6 at Stadio Monigo in round one. Treviso had a won 2, lost 6 record against Irish provinces last season, with both victories coming away from home in Belfast and Galway. Treviso's only previous win against Munster was 19-18 at Stadio Monigo in February 2011.
Munster: 15 Denis Hurley, 14 Doug Howlett (capt), 13 Casey Laulala, 12 James Downey, 11 Luke O'Dea, 10 Ian Keatley, 9 Duncan Williams, 8 James Coughlan, 7 Sean Dougall, 6 Dave O'Callaghan, 5 Billy Holland, 4 Donncha O'Callaghan, 3 Stephen Archer, 2 Damien Varley, 1 Wian du Preez.
Replacements: 16 Mike Sherry, 17 Dave Kilcoyne, 18 BJ Botha, 19 Dave Foley, 20 Paddy Butler, 21 Peter Stringer, 22 Scott Deasy, 23 Ivan Dineen.
Treviso: 15 Brendan Williams, 14 Ludovico Nitoglia, 13 Alberto Sgarbi, 12 Luca Morisi, 11 Tommaso Iannone, 10 Alberto Di Bernardo, 9 Edoardo Gori, 8 Paul Derbyshire, 7 Dean Budd, 6 Simone Favaro, 5 Valerio Bernab˛, 4 Antonio Pavanello (capt), 3 Lorenzo Cittadini, 2 Enrico Ceccato, 1 Michele Rizzo.
Replacements: 16 Giovanni Maistri, 17 Alberto De Marchi, 18 Ignacio Fernandez-Rouyet, 19 Corniel Van Zyl, 20 Robert Barbieri, 21 Alessandro Zanni, 22 Fabio Semenzato, 23 Kristopher Burton.
Date: Friday, September 7
Kick-off: 20:00 BST
Venue: Thomond Park, Limerick
Referee: Andrew McMenemy (Scotland)
Assistant referees: Peter Haycock (Ireland), David Keane (Ireland)
Television match official: Sean Flannery (Ireland)