Harlequins ran in four tries to record a 37-13 bonus-point win over Worcester at Sixways on Friday.
Harlequins produced a brilliant display of 15-man rugby to destroy Warriors and get back to winning ways.
Conor O'Shea's side recovered from going behind to an early Ignacio Mieres penalty to totally dominate the contest thereafter.
Worcester played the first hour of the match a man down after their ill-discipline and desperation to keep on-song Harlequins at bay saw them lose Jake Abbott, Ed Shervington and Sam Matavesi to the sin-bin.
Matavesi's return to the field inspired something of a Worcester comeback as the match approached the final quarter, but the Warriors were well beaten by then by a Harlequins outfit that looked to offload at every opportunity.
The only surprise in a thoroughly one-sided first half was that it took half an hour before the Londoners breached the Worcester defence.
With a minute left on Abbott's sin-binning, Chris Robshaw's fed Danny Care and the scrum-half sped home from 35 metres to score under the posts with 30 minutes on the clock.
Care's score and Nick Evans' subsequent conversion made it 13-6 with Evans having earlier kicked two penalties following Mieres's initial strike.
A rampant Joe Marler burrowed over from close range to cap a fine first half display with a try. Evans added the extras to make the half-time score 20-6 to Quins.
Worcester started the second period with 14 men after Shervington had been yellow-carded three minutes before the break.
And Quins wasted no time scoring their third try, Mike Brown's quick hands putting hooker Rob Buchanan away in the corner.
Evans kicked the touchline conversion and then added the extras to a Brown try on 49 minutes to put the result beyond any doubt.
Quins lost replacement prop Mark Lambert to a yellow-card on 63 minutes and Worcester made the extra man count when they were awarded a penalty try by referee Wayne Barnes following repeated infringements.
Try: Penalty try
Pens: Mieres 2
Yellow cards: Abbott, Shervington, Matavesi
Tries: Care, Marler, Buchanan, Brown
Cons: Evans 4
Pens: Evans 2, Botica
Yellow card: Lambert
Worcester: 15 Chris Pennell, 14 Josh Drauniniu, 13 Ravai Fatiaki, 12 Josh Matavesi, 11 David Lemi, 10 Ignacio Mieres, 9 Paul Hodgson, 8 Jonathan Thomas (c), 7 Jake Abbott, 6 Sam Betty, 5 Dean Schofield, 4 Mike Williams, 3 John Andress, 2 Ed Shervington, 1 Jeremy Becasseau.
Replacements: 16 Nick Seymour, 17 Paul Andrew, 18 Euan Murray, 19 Chris Jones, 20 Semisi Taulava, 21 Jeremy Su'a, 22 Danny Gray, 23 Jon Clarke.
Harlequins: 15 Mike Brown, 14 Tom Williams, 13 George Lowe, 12 Tom Casson, 11 Ugo Monye, 10 Nick Evans, 9 Danny Care, 8 Tom Guest, 7 Chris Robshaw (c), 6 Maurie Fa'asavalu, 5 George Robson, 4 Nick Easter, 3 Will Collier, 2 Rob Buchanan, 1 Joe Marler.
Replacements: 16 Dave Ward, 17 Mark Lambert, 18 Kyle Sinckler, 19 George Merrick, 20 Luke Wallace, 21 Karl Dickson, 22 Ben Botica, 23 Sam Smith.
Referee: Wayne Barnes
Assistant referees: Robin Goodliffe, Paul Dix
Television match official: Geoffrey Warren