Edinburgh have suffered a major blow on the eve of their Heineken Cup clash at Munster with Scotland wing Tim Visser ruled out with a knee injury.
Frequent finisher Visser sustained the problem in last weekend's Pool One defeat to Saracens and has failed a fitness test on Saturday morning.
He is replaced by Tom Brown, with Dougie Fife taking the space vacated on the bench.
Edinburgh (revised): 15 Greig Tonks, 14 Lee Jones, 13 Nick De Luca, 12 Ben Atiga, 11 Tom Brown, 10 Gregor Hunter, 9 Richie Rees, 8 Netani Talei, 7 Stuart McInally, 6 David Denton, 5 Sean Cox, 4 Grant Gilchrist, 3 Geoff Cross, 2 Ross Ford, 1 John Yapp.
Replacements: 16 Andy Titterrell, 17 Robin Hislop, 18 Willem Nel, 19 Rob McAlpine, 20 Dimitri Basilaia, 21 Chris Leck, 22 Matt Scott, 23 Dougie Fife.
Date: Sunday, October 21
Venue: Thomond Park, Limerick
Kick-off: 12.45 BST (11:45 GMT)
Referee: Wayne Barnes