Argentina centre Juan MartÃn HernÃ¡ndez has been ruled out his country's match against South Africa at Loftus Versfeld in Pretoria.
HernÃ¡ndez was scheduled to start at inside centre, charged with the task of sparking the backline of los Pumas into life.
But the 32-year-old, who is currently without a club after leaving Racing MÃ©tro, has withdrawn before kickoff, replaced by Santiago GonzÃ¡lez Iglesias.
JerÃ³nimo de la Fuente has come onto the bench.
Argentina (revised): 15 JoaquÃn Tuculet, 14 Horacio Agulla, 13 Marcelo Bosch, 12 Santiago GonzÃ¡lez Iglesias, 11 Manuel Montero, 10 NicolÃ¡s SÃ¡nchez, 9 MartÃn Landajo, 8 Juan Manuel LeguizamÃ³n, 7 Juan MartÃn FernÃ¡ndez Lobbe, 6 Pablo Matera, 5 TomÃ¡s Lavanini, 4 Mariano Galarza, 3 Ramiro Herrera, 2 AgustÃn Creevy (c), 1 Marcos Ayerza.
Replacements: 16 MatÃas Cortese, 17 Lucas Noguera Paz, 18 Nahuel Tetaz Chaparro, 19 MatÃas Alemanno, 20 Leonardo Senatore, 21 TomÃ¡s Cubelli, 22 JerÃ³nimo de la Fuente, 23 Lucas GonzÃ¡lez Amorosino.