Argentina replacement back Juan Imhoff has been ruled out of Saturday's match against South Africa due to injury.
The Racing Métro flyer sustained a quad injury to his leg in training on Thursday.
Imhoff started last weekend against South Africa but was replaced in the starting line-up by Bath winger Horacio Agulla.
The injury is expected to sideline Imhoff for two weeks, ruling him out of Argentina's following match against the All Blacks in Hamilton.
Imhoff has now been replaced amongst the substitutes by Grenoble utility back Joaquin Tuculet.
Argentina: 15 Lucas Gonzalez Amorosino, 14 Gonzalo Camacho, 13 Marcelo Bosch, 12 Felipe Contepomi (captain), 11 Horacio Agulla, 10 Nicolás Sánchez, 9 Martín Landajo, 8 Leonardo Senatore, 7 Juan Manuel Leguizamón, 6 Pablo Matera, 5 Mariano Galarza, 4 Julio Farías Cabello, 3 Juan Figallo, 2 Eusebio Guiñazú,1 Marcos Ayerza.
Replacements: 16 Agustín Creevy, 17 Nahuel Lobo, 18 Tomas Lavaninni, 19 Benjamin Macome, 20 Tomás Cubelli, 21 Santiago Fernández, 22 Joaquin Tuculet.
Date: Saturday, August 24
Venue: Estadio Malvinas Argentinas, Mendoza
Kick-off: 16.10 (19.10 GMT)
Referee: Steve Walsh (Australia)
Assistant referees:John Lacey (Ireland), Pascal Gauzère (France)
TMO: Marshall Kilgore (Ireland)