Ulster fly-half Paddy Jackson will start for Ireland in place of the injured Johnny Sexton against Scotland in the Six Nations.
Jackson is preferred to Ireland stalwart Ronan O'Gara, who is named amongst the replacements.
Six other changes see the uncapped Luke Marshall named at inside centre in place of the injured Gordon D'Arcy, whilst Ulster prop Tom Court also starts as a replacement for the suspended Cian Healy.
Keith Earls comes onto the left wing to replace the injured Simon Zebo, whilst Donnacha O'Callaghan starts in the second row alongside Donnacha Ryan.
Leinster lock Devin Toner and Ulster back row Iain Henderson are named on the bench.
More to follow...
Ireland: 15 Rob Kearney, 14 Craig Gilroy, 13 Brian O'Driscoll, 12 Luke Marshall, 11 Keith Earls, 10 Paddy Jackson, 9 Conor Murray, 8 Jamie Heaslip (c), 7 Sean O'Brien, 6 Peter O'Mahony, 5 Donnacha Ryan, 4 Donnacha O'Callaghan, 3 Mike Ross, 2 Rory Best, 1 Tom Court.
Replacements: 16 Sean Cronin, 17 Dave Kilcoyne, 18 Declan Fitzpatrick, 19 Devin Toner, 20 Iain Henderson, 21 Eoin Reddan, 22 Ronan O'Gara, 23 Luke Fitzgerald.
Date: Sunday, 24 February
Kick-off: 14:00 GMT
Referee: Wayne Barnes (England)
Assistant referees: JÃ©rÃ´me Garces (France), Greg Garner (England)
Television match official: Eric Gauzins (France)