Brian O'Driscoll and Sean O'Brien are both expected to be fit to start for Ireland in Sunday's Six Nations clash against Scotland at Murrayfield.
Both returned to full training on Tuesday having picked up injuries (ankle and hamstring resepectivley) in the 12-6 defeat to England in Dublin.
Uncapped centre Luke Marshall should be able to replace the injured Gordon D'Arcy after recovering from the dead leg suffered on duty for Ulster last Friday.
Second row Donnacha Ryan is however doubtful having taken only limited part in training due to a back spasm.
"Brian and Sean trained this morning and are expected to be fully involved for the rest of the week," said team manager Mick Kearney.
"Donnacha continues to recover from a back spasm. He took part in some of the session today and we're continuing to monitor his rehab.
"Luke Marshall has recovered really well from his dead leg and trained fully this morning. There are no concerns about him."
Kearney admitted that Ireland are still considering an appeal over Cian Healy's three-week suspension give that, in effect, it rules him out for four weeks.
"My own view is that there was a certain degree of ambiguity in the hearing's decision," said Kearney.
"While Cian was suspended for three weeks, he was ruled out of rugby for four weeks. That's an area we'd like clarity on.
"But unless we feel we have very good grounds for appeal, we won't appeal it."
Head coach Declan Kidney will name his team to face Scotland on Wednesday.