Toulouse left the Stade Yves du Manoir without scoring a point as Montpellier romped to a 25-0 win on Sunday.
The five-time European champions were off the boil for their visit to play Fabien Galthié's side, as the trend of poor performances from teams away from home in the Top 14 continued.
Toulouse had comfortably swept aside Racing Métro in midweek with a 30-6 win at home, with Montpellier securing a late 36-29 victory away to Bordeaux-Begles.
Despite the handsome margin of Montpellier's victory, neither side scored any points until the half-hour mark.
Scrum-half Jonathan Pélissié missed a long-range penalty in the 26th minute but was then on hand to score the first try of the match. The new signing from Grenoble dummied his way through a half gap and sped away for an impressive try.
Montpellier have already had numerous try chances disallowed this season, including four against Biarritz, and their luck was again absent with full-back Anthony Floch's effort ruled out shortly after Pélissié went over.
Pélissié added another penalty on the stroke of half-time, to give the hosts a 10-0 lead at the break.
Toulouse struggled to slot into gear throughout as their attack stuttered, Luke McAlister at times struggling to find the wavelength of his team-mates.
Floch added a penalty in the 51st minute as Montpellier's lead increased, former France centre Florian Fritz sent to the sin bin after consultation from the TMO for a shirt pull on Fulgence Ouedraogo.
Floch was involved again for Montpellier's second try - not to be denied by the TMO for a second time, the full-back pounced after a horrendous mix up by Maxime Médard and Yoann Huget in their own try area.
A breakaway score then confirmed the result - replacement Benoit Sicart cantering away from the defence after combining with Ouedraogo and Timoci Nagusa to a rapturous reception from the home fans.
Toulouse battered away at the hosts' defensive line during the closing stages desperate for something to show for their efforts, but it wasn't to be.
Instead Montpellier move momentarily top of the league, until Clermont play later on Sunday.
Tries: Pélissié, Floch, Sicart
Cons: Pélissié, Paillaugue
Pens: Pélissié, Floch
Yellow Card: Fritz
Montpllier: 15 Anthony Floch, 14 Yoan Audrin, 13 Anthony Tuitavake, 12 Wynand Olivier, 11 Timoci Nagusa,10 Francois Trinh-Duc, 9 Jonathan Pelissie, 8 Alex Tulou, 7 Alexandre Bias, 6 Fulgence Ouedraogo, 5 Thibaut Privat, 4 Mickael de Marco, 3 Nicolas Mas, 2 Mickael Ivaldi, 1 Yvan Watremez
Replacements: 16 Charles Geli, 17 Leleimalefaga, 18 Robins Tchale Watchou, 19 John Beattie, 20 Benoit Paillaugue, 21 Thomas Combezou, 22 Benoit Sicart, 23 Maximiliano Bustos
Toulouse: 15 Yoann Huget, 14 Maxime Medard, 13 Yann David, 12 Florian Fritz, 11 Hosea Gear, 10 Luke McAlister, 9 Jean Marc Doussain, 8 Louis Picamoles, 7 Thierry Dusautoir, 6 Yannick Nyanga, 5 Joe Tekori, 4 Romain Millo Chlusky, 3 Census Johnston, 2 Christopher Tolofua, 1 Schalk Ferreira.
Replacements: 16 Martinus Jacobus van der Heever, 17 Cyril Baille, 18 Dorian Aldegheri, 19 Yoann Maestri, 20 Yacouba Camara, 21 Gillian Galan, 22 Sebastien Bezy, 23 Lionel Beauxis
Referee: Paul Gauzere