Nick Phipps and Luke Jones both return to the Rebels starting side for Friday's Super Rugby clash with the Waraths at AAMI Park.
Phipps takes over from Nic Stirzaker while Jones starts ahead of Cadeyrn Neville.
James O'Connor was unable to return early from injury after the decision was made by the medical staff not to risk the 23 year old.
Rebels High Performance Manager, Mark Andrews said the risk was too great at this early stage.
"James was desperate to play, which was admirable," said Andrews.
"However it would not be in the team's or player's best interest to risk further damage when the injury is a significant one, and has not fully healed."
Rebels: 15 Jason Woodward, 14 Tom English, 13 Mitch Inman, 12 Rory Sidey, 11 Lachlan Mitchell, 10 Bryce Hegarty, 9 Nick Phipps, 8 Scott Higginbotham (c), 7 Scott Fuglistaller, 6 Jarrod Saffy, 5 Luke Jones, 4 Hugh Pyle, 3 Laurie Weeks, 2 Ged Robinson, 1 Nic Henderson
Replacements:16 Shota Horie, 17 Paul Alo-Emile, 18 Cadeyrn Neville, 19 Gareth Delve, 20 Nic Stirzaker, 21 James Hilgendorf, 22 Kimami Sitauti
Date: Friday May 24,
Venue: AAMI Park, Melbourne
Kick-off: 19.40 (09.40 GMT)
Referee: Garratt Williamson (New Zealand)