France coach Philippe Saint-André has made three changes to his starting XV for this Saturday's Test against Samoa at the Stade de France in Paris.
World Cup finalist Morgan Parra is promoted from the bench, swapping places with Maxime Machenaud at scrum-half.
Both the other changes are in the front row, where hooker Benjamin Kayser and Thomas Domingo take over from Dimitri Szarzewski and Yannick Forestier, who are amongst the replacements as Saint-André keeps the same matchday 23 that beat Argentina last week.
Saint-André said that he viewed the match against Samoa as the most important and potentially hazardous of the three games in the autumn Test series.
"We were the outsiders against Australia, it was 50-50 against Argentina and now we are in the role of favourites," he said.
"We will see if we are capabale of assuming that mantle and once again winning. We are trying to instill a culture of quality and consistency at the topmost level. That is the challenge that awaits us on Saturday."
"We know that traditionally in French rugby we prefer being the outsiders rather than the favourites. Now it is time to step up to the plate.
"We are fourth in the IRB world rankings and Samoa are ninth, so we can hardly consider ourselves as the outsiders this time.
"Samoa, though, are a team who are making giant strides forward. They are tough in the contact area, very aggressive and they have improved in the areas of collective organisation, defence and at the breakdown.
"It is up to us to produce the goods and enable us to make it three wins in a row."
A win over Samoa would give France a clean sweep of their autumn internationals against southern hemisphere sides for the first time since 2005 and ensure that they remain in the top band of four seeds for next month's 2015 World Cup draw in England.
France: 15 Brice Dulin, 14 Wesley Fofana, 13 Florian Fritz, 12 Maxime Mermoz, 11 Vincent Clerc, 10 Frederic Michalak, 9 Morgan Parra, 8 Louis Picamoles, 7 Fulgence Ouedraogo, 6 Yannick Nyanga, 5 Yoann Maestri, 4 Pascal Papé (c), 3 Nicolas Mas, 2 Benjamin Kayser, 1 Thomas Domingo
Replacements: 16 Dimitri Szarzewski, 17 Yannick Forestier, 18 Vincent Debaty, 19 Jocelino Suta, 20 Damien Chouly, 21 Maxime Machenaud, 22 Francois Trinh-Duc, 23 Yoann Huget.
Date: Saturday, November 24
Venue: Stade de France, Paris
Kick-off: 20.00 local (19.00 GMT)
Referee: John Lacey (Ireland)