Incumbent Edinburgh head and assistant coaches Michael Bradley and Neil Back have left their posts with immediate effect
Bradley and Back having agreed terms to bring their contracts to an early end - Bradley's was due to expire this May, and Back the following season.
Bradley famous lead Edinburgh to the Heineken Cup semi-finals last season, the first time a Scottish side has ever reached the last four of the competition.
Scotland assistant coaches Stevie Scott and Duncan Hodge have been appointed as interim coaches. Scott and Hodge remain committed to the Six Nations campaign, and will take the reins as head and assistant coach of the capital club after the competition's conclusion.
"We feel this move is necessary to give a fresh impetus to the squad going into the remainder of the season," said Scottish Rugby Chief Executive Mark Dodson
"Our search for a new coaching team for Edinburgh Rugby continues, with a view to getting the club back on a winning track."
"I'd like to thank Michael and Neil for all of their input and wish them the very best in the future," said Edinburgh managing director, Craig Docherty.
"It's heartening to welcome the appointment of two former Edinburgh and Scotland internationalists to our back-room on an interim basis.
"I believe they are the right people to inspire our squad for the remainder of the season and assess the player group going forward."
"I'm delighted to be given this opportunity for the rest of the season," said Edinburgh interim head coach, Stevie Scott.
"Naturally the big thing for me at the moment is my commitment to the national team but, come a week on Saturday night in Paris, I'll be straight into Edinburgh mode and will be working with Duncan [Hodge] to get the players ready for the home match against Ulster and the rest of the season."