Stalwart prop Greg Holmes will play his 100th match for the Reds in Friday's Super Rugby clash with the Sharks at Suncorp Stadium.
29-year-old Holmes will become the 26th Reds player to join the prestigious 100-caps club when he lines up at loosehead.
Reds Director of Coaching Ewen McKenzie named a 22-man squad on Wednesday rather than a starting XV, but confirmed the prop player would start.
Holmes becomes just the third Reds prop to reach the century mark after Dan Crowley (124) and Sam Pilecki (122), and the first since former captain John Roe in 2008.
"It's quite humbling when you think about the calibre of players who have played 100 games for Queensland and the service they have given to the Reds," he said.
Wallabies' winger Dom Shipperley has succumbed to a lingering back injury to be the only change to the Reds squad, with Rod Davies returning from a hamstring twinge.
McKenzie will announce his team on Thursday but hinted there would be more changes on top of the likely return of Davies and tight-head prop James Slipper after the 11-11 draw with Western Force.
Backs: Jono Lance, Rod Davies, Anthony Faingaa, Ben Tapuai, Digby Ioane, Quade Cooper, Will Genia, Ben Lucas, Chris Feauai-Sautia.
Forwards: Jake Schatz, Liam Gill, Ed Quirk, Beau Robinson, Jarrad Butler, Ed O'Donoghue, James Horwill, Rob Simmons, James Slipper, Saia Faingaa, James Hanson, Greg Holmes, Albert Anae.