The Brumbies have named their side that will face the Rebels in Friday's Super Rugby clash in Canberra, with Pat McCabe installed at inside centre.
Head coach Jake White has made eight changes to his 22-man squad - including five to the starting XV - to take on the dangerous Melbourne outfit.
With the absence of five Wallabies players and a shoulder dislocation to Fotu Auelua, the Brumbies have re-jigged the forward pack to include Leon Power at lock, Scott Fardy at blindside flanker and Peter Kimlin at number eight.
Siliva Siliva will start at hooker and Dan Palmer returns to the starting side at tighthead prop.
Also returning to the starting side is Wallaby McCabe at inside centre in place of Christian Lealiifano. Clyde Rathbone slides onto Joe Tomane's wing and the rest of last week's backline remains intact.
The bench includes first time Brumby, Josh Mann-Rea as hooker back-up, Etienne Oosthuizen at lock and Zack Holmes in jersey number 22.
Head coach White said the side was good enough to cement the club's top-of-the-log standings but would need to dig deep for a result on Friday.
"The Wallabies tour has forced quite a few changes but the guys we have selected have been involved with the squad for a year now and know their jobs," White said.
"It's comforting to be able to bring in proven Wallabies like Clyde [Rathbone] and Pat [McCabe]. We'll be looking for plenty of involvement from both of those guys.
"The Rebels have proven over the last month they are a genuine threat. Last week they had the Reds under the pump for 90 per cent of the match so we are fully aware of the challenge that lies ahead."
As announced earlier in the week, Nic White becomes the Brumbies twelfth and youngest captain when he leads the side out against the Rebels. White made his first appearance at Canberra Stadium in this corresponding fixture two years ago and will be looking to make it 3-0 against Melbourne in Canberra on Friday.
Brumbies: 15 Jesse Mogg, 14 Henry Speight, 13 Tevita Kuridrani, 12 Pat McCabe, 11 Clyde Rathbone, 10 Matt Toomua, 9 Nic White (c), 8 Peter Kimlin, 7 Colby Faingaa, 6 Scott Fardy, 5 Sam Carter, 4 Leon Power, 3 Dan Palmer, 2 Siliva Siliva, 1 Scott Sio.
Replacements: 16 Josh Mann-Rea, 17 Ruan Smith, 18 Etienne Oosthuizen, 19 Jordan Smiler, 20 Ian Prior, 21 Robbie Coleman, 22 Zack Holmes.
Date: Friday, June 7
Kick-off: 19:40 (9:40 GMT)
Venue: Canberra Staduim, Canberra
Referee: Rohan Hoffmann (Australia)
Assistant referees: Steve Walsh (Australia), Matt O'Brien (Australia)
Television match official: George Ayoub (Australia)