England have received a mixed bag of injury news ahead of Saturday's Six Nations decider against Wales at the Millennium Stadium.
Number eight Ben Morgan has been ruled due to an ankle injury suffered during the opening-day victory over Scotland but fly-half Owen Farrell is fit to train having recovered from his quad injury and is expected to start.
There are however also concerns over the fitness of forwards Geoff Parling (shoulder), Joe Launchbury (elbow) and Courtney Lawes (arm).
"Ben will stay at Gloucester this week. We knew his ankle would take six to eight weeks and he won't make it in time," said head coach Stuart Lancaster.
England were given a wake up call at Twickenham on Sunday when they scraped to an 18-11 victory over Italy in what was easily their worst performance of the championship.
"We have had a chance to review the game and there were lots of areas we were pleased with, but I wouldn't call it a blessing in disguise," said Lancaster.
"I'm not of the mindset as a coach that I'd want to not get areas right in order to get ourselves in the right place to play a game. We've definitely got plenty to work on.
"It's a massive game because of the context of the result, which is huge for both teams," he added.
"We're a young team and a lot of our players haven't played there before, so going to that type of environment is exactly the test we want.
"It's a couple of years until 2015 and we know that we've got Wales in what will be a big high-pressure game.
"For a team to get that type of experience now and go up there and try to win a Grand Slam will be a special occasion."