London Irish have made two changes and a positional switch to their team that welcomes Worcester to the Madejski Stadium on Sunday.
Both sides have claimed two wins from there opening five games and a victory this weekend will come as a welcome boost.
In his search to achieve this, Exiles boss Toby Booth has tinkered with his pack.
Declan Danaher starts at blindside flanker with Bryn Evans moving in to the second row in place of James Sandford. Faan Rautenbach comes in at tighthead prop with Max Lahiff dropping to the bench.
Worcester coach Richard Hill has made just one alteration to the team that beat Northampton last time out.
With scrum-halves Shaun Perry and Jonny Arr both ruled out of action with knee injuries, Ollie Frost makes his first Premiership start.
Hill is well aware of the importance of the game.
"We are coming to the tough end of six back to back Aviva Premiership games," he explained.
"It has been a survival of the fittest after five pretty intense games.
"We now need one big last effort and if we can win three of the first six games then that will be a good achievement."
London Irish: 15 Tom Homer, 14 Topsy Ojo, 13 Jonathan Joseph, 12 Steve Shingler, 11 Adam Thompstone, 10 Dan Bowden, 9 Darren Allinson, 8 Chris Hala'ufia 7 Alex Gray, 6 Declan Danaher, 5 Bryn Evans , 4 Nick Kennedy, 3 Faan Rautenbach, 2 David Paice, 1 Clarke Dermody (c)
Replacements: 16 James Buckland, 17 Mark George, 18 Max Lahiff, 19 David Sisi, 20 Jamie Gibson, 21 Guy Armitage, 22 Adrian Jarvis, 23 Paul Hodgson
Worcester: 15 Errie Claassens, 14 Marcel Garvey, 13 Alex Grove, 12 Dale Rasmussen (c), 11 Miles Benjamin, 10 Andy Goode, 9 Ollie Frost, 8 Chris Jones, 7 Jake Abbott, 6 Neil Best, 5 Craig Gillies, 4 James Percival, 3 Tevita Taumoepeau, 2 Ed Shervington, 1 Matt Mullan.
Replacements: 16 Ceri Jones, 17 Chris Fortey, 18 Oliver Tomaszczyk, 19 Adam Balding, 20 Matt Kvesic, 21 Danny Gray, 22 Joe Carlisle, 23 Tom Arscott.
Date: Sunday, October 8
Kick-off: 14:00 (13:00 GMT)
Venue: Madejski Stadiumb
Referee: JP Doyle