Sale have named Josh Beaumont, the son of former England player Bill, at number eight for their Heineken Cup Pool clash with Montpellier on Friday.
Openside Dave Seymour returns as captain.
Whilst Sale's chances of qualification have gone after back to back defeats to Toulon, they are eager to finish with a flourish and hopefully earn ranking points for future years in the competition.
Mark Cueto, who levelled the Premiership try-scoring record against Worcester moves to centre and plays alongside Mark Jennings who scored a try in the opening round against Cardiff Blues.
Meanwhile, Montpellier have recalled respective France and Argentina international forwards Fulgence Ouedraogo and Agustin Creevy to their side while Francois Trinh-Duc leads the backline.
Sale Sharks: 15 Cameron Shepherd, 14 Tom Brady, 13 Mark Cueto, 12 Mark Jennings, 11 Charlie Amesbury, 10 Danny Cipriani, 9 Will Cliff, 8 Josh Beaumont, 7 David Seymour, 6 James Doyle, 5 Tom Holmes, 4 Richie Gray, 3 Vadim Cobilas, 2 Marc Jones, 1 Aston Croall.
Replacements: 16 Tom Cruse, 17 Ross Harrison, 18 Tony Buckley, 19 Kearnan Myall, 20 Tommy Taylor, 21 Nathan Fowles, 22 Rob Miller, 23 Jordan Davies.
Montpellier: 15 Pierre BÃ©rard, 14 Timoci Nagusa, 13 Thomas Combezou, 12 Santiago Fernandez, 11 Yohann Artru, 10 Francois Trinh-Duc, 9 Benoit Paillaugue, 8 Johnnie Beattie, 7 Mamuka Gorgodze, 6 Fulgence Ouedraogo, 5 Aliki Fakate, 4 Mickael Demarco, 3 Maximiliano Bustos, 2 Agustin Creevy, 1 Mikheil Nariashvili.
Replacements: 16 Rassie van Vuuren, 17 Yvan Watremez, 18 Barry Fa'amausili, 19 RÃ©my Martin, 20 Alexandre Bias, 21 Eric Escande, 22 Paul Bosch, 23 Lucas Amorosino.
Date: Friday, January 11
Venue: Salford City Stadium
Referee: Leighton Hodges (Wales)
Assistant referees: Rhys Thomas (Wales), Wayne Davies (Wales)
Timekeeper: Mike Hamlin (England)
Citing commissioner: Gwyn Bowden (Wales)
Assessor: Andy Clift (Scotland)