Newport Gwent Dragons secured a 20-8 victory over London Wasps in the early match on Saturday.
The win for Lyn Jones' team came courtesy of two tries from wingers Matthew Pewtner and Ashton Hewitt.
Gloucester meanwhile ran in two tries to see off Newcastle Falcons at Kingsholm.
Newport Gwent Dragons 20-8 London Wasps
Gloucester 20-3 Newcastle Falcons
Ashton Hewitt's 71st-minute try sealed a 20-8 win for Newport Gwent Dragons over visiting Aviva Premiership side London Wasps.
Rhys Jones, who was a late replacement for full-back Hallam Amos, kicked two conversions and two penalties.
Jones opened the scoring in the second minute with a three-pointer before Wasps' Joe Carlisle responded for Dai Young's team.
Neil Cochrane's try in the 27th minute put Wasps ahead 8-6 for the only time in the match, but it didn't last long as Matthew Pewtner crossed for the Dragons before Hewitt finished things off late on.
Tries: Pewtner, Hewitt
Cons: R.Jones 2
Pens: R.Jones 2
Dragons: 15 Rhys Jones, 14 Ashton Hewitt, 13 Tyler Morgan, 12 Ashley Smith, 11 Matthew Pewtner, 10 Steffan Jones, 9 Jonathan Evans, 8 Ieuan Jones. 7 James Benjamin, 6 Netani Talei, 5 Robert Sidoli (c), 4 Cory Hill, 3 Nathan Buck, 2 Hugh Gustafson, 1 Phil Price.
Replacements: 16 Elliot Dee, 17 Aaron Coundley, 18 Dan Way, 19 Joe Davies, 20 Scott Matthews, 21 Luc Jones, 22 Dorian Jones, 23 Will Harries.
Wasps: 15 Tommy Bell, 14 Jonah Holmes, 13 Ben Jacobs, 12 Chris Bell (c), 11 Tom Howe, 10 Joe Carlisle, 9 Jack Moates, 8 Sam Jones, 7 Matt Everard, 6 James Haskell, 5 James Cannon, 4 Esteban Lozada, 3 Phil Swainston, 2 Neil Cochrane, 1 Ricky Reeves.
Replacements: 16 Carlo Festuccia, 17 Simon McIntyre, 18 Will Taylor, 19 Kearnan Myall, 20 Ed Jackson, 21 Joe Simpson, 22 Andy Goode, 23 Charlie Hayter
Referee: Steve Lee (England)
Assistant referees: Sean Brickell (Wales), Craig Evans (Wales)
Gloucester saw off the threat of Dean Richards' Newcastle Falcons thanks to two tries in either half from their backs.
Full-back Rob Cook opened the scoring with a try in the eighth minute with England fly-half Freddie Burns converting.
Rory Clegg scored the Falcons' only points with a penalty shortly afterwards, but from then on Newcastle were left to watch Gloucester tick the scoreboard over.
Burns added a penalty either side of half-time before Mike Tindall's try in the 61st minute confirmed the result.
Tries: Cook, Tindall
Cons: Burns 2
Pens: Burns 2
Yellow Card: Knight
Yellow Card: Vickers
Gloucester: 15 Martyn Thomas, 14 James Simpson-Daniel, 13 Mike Tindall, 12 Ryan Mills, 11 Jonny May, 10 Freddie Burns, 9 Dan Robson, 8 Matt Cox, 7 Andy Hazell, 6 Ross Moriarty, 5 Tom Savage (c), 4 Elliott Stooke, 3 Shaun Knight, 2 Huia Edmonds, 1 Nick Wood
Replacements: 16 Dan George, 17 Yann Thomas, 18 Rupert Harden, 19 Will James, 20 Lewis Ludlow, 21 Jimmy Cowan, 22 Billy Burns, 23 Rob Cook
Newcastle: 15 Alex Tait, 14 Noah Cato, 13 Danny Barnes, 12 Adam Powell, 11 Ryan Shortland, 10 Rory Clegg, 9 Warren Fury, 8 Ally Hogg, 7 Will Welch (c), 6 Richard Mayhew, 5 Dom Barrow, 4 Carlo del Fava, 3 Scott Wilson, 2 George McGuigan, 1 Rob Vickers
Replacements: 16 Kieran Brookes, 17 Gary Strain, 18 Grant Shiells, 19 Scott MacLeod, 20 Mark Wilson, 21 Mike Blair, 22 Zach Kibirige, 23 Phil Godman
Referee: Neil Hennessy (Wales)
Assistant referees: Roger Baileff (England), Andrew Pearce (England)
Timekeeper: Tony Turner (England)