Sale Sharks have named their squad to play Harlequins in Edgeley Park's final game hosting them on Saturday.
Fifteen of the squad were on duty at Gloucester two weeks ago in the Aviva Premiership clash.
Sale will have two players making their senior debuts for the club: Tommy Bell, who has been at Leeds Carnegie through the season and has recently been named for the England U20 party in South Africa, and Will Bordill, from Sandbach but of Scottish descent. Bordill has played for Scotland's U20 side this season, and has appeared for Preston Grasshoppers along with flanker Billy Emerson, who is named on the bench and is also lined up for his debut.
All four of the players who have been at Leeds Carnegie this season - Bell, Jordan Davies, Will Cliff and Iain Thornley - are included in the 23. Andrew Sheridan, moving to Toulon next season, misses the game through injury, but Northampton-bound Luther Burrell starts at centre.
"There is plenty to play for on Saturday. We'll have a youthful team to try and combat the way that Harlequins play. There should be a large crowd to see us say farewell to Edgeley Park and we are all looking forward to it," said Sharks' Chief Executive Steve Diamond.
Meanwhile, Harlequins go into the final round of Aviva Premiership action against Sale knowing that a win will seal first place and a semi- final at the Stoop on May 12.
Mike Brown starts at full-back, with Tom Williams and Sam Smith partnering in the back three. Ugo Monye is undergoing further treatment following his injury against Leicester and will be reassessed early next week. Jordan Turner-Hall and George Lowe are in the centre.
Joe Gray returns at hooker to make his 50th appearance. Gray is the only change from the pack that faced Leicester. Joe Marler and James Johnston start at prop as Olly Kohn and George Robson combine at lock. Captain Chris Robshaw starts to make his 100th Premiership appearance, with Maurie Fa'asavalu and Nick Easter completing the back row.
Rob Buchanan, Mark Lambert and Will Collier will look to impact in the front row, with Tomas Vallejos and Tom Guest ready to cover in the back five. Karl Dickson and Rory Clegg provide specialist half back cover and Matt Hopper offers cover for the rest of the backline.
Form: Sale Sharks require just one match point to qualify for next season's Heineken Cup. The Sharks have won successive Aviva Premiership Rugby matches against Bath and Gloucester. Edgeley Park hosts it's 99th and final Premiership game before Sale move to the City of Salford Stadium. Harlequins have already reached a second Premiership semi-final but still require three points to guarantee that it will be played on home soil. Quins' only away win so far in 2012 was 24-19 against Saracens at Wembley Stadium on 31 March. The last seven clashes between the two clubs in the Premiership have all been won by the home side on the day. Quins have already won at Edgeley Park this season, with a 37-25 victory in the Anglo-Welsh Cup on 21 October. The Londoners only previous win at the venue in the Premiership came on 19 November 2004.
Sale Sharks: 15 Rob Miller, 14 Tom Brady, 13 Will Addison, 12 Luther Burrell, 11 Mark Cueto, 10 Tommy Bell, 9 Scott Mathie, 8 Mark Easter, 7 David Seymour (capt), 6 Will Bordill, 5 Tom Holmes, 4 Kearnan Myall, 3 Henry Thomas, 2 Marc Jones, 1 Lee Imiolek.
Replacements: 16 Tommy Taylor, 17 Ross Harrison, 18 Joe Ward, 19 Billy Emerson, 20 Jordan Davies, 21 Will Cliff, 22 Iain Thornley, 23 Charlie Amesbury.
Harlequins: 15 Mike Brown, 14 Tom Williams, 13 George Lowe, 12 Jordan Turner-Hall, 11 Sam Smith, 10 Nick Evans, 9 Danny Care, 8 Nick Easter, 7 Chris Robshaw (capt), 6 Maurie Fa'asavalu, 5 George Robson, 4 Olly Kohn, 3 James Johnston, 2 Joe Gray, 1 Joe Marler.
Replacements: 16 Rob Buchanan, 17 Mark Lambert, 18 Will Collier, 19 Tomas Vallejos, 20 Tom Guest, 21 Karl Dickson, 22 Rory Clegg, 23 Matt Hopper.
Date: Saturday, May 5
Venue: Edgeley Park
Kick-off: 14:00 (13:00 GMT)
Referee: Martin Fox
Assistant referees: Alan Biggs, Paul Burton