London Welsh will be chasing a third consecutive Premiership win when they welcome the Cherry and Whites to the Kassam Stadium on Sunday.
Exiles coach Lyn Jones makes one change to the starting line-up that beat Sale 29-19 - a result that saw Welsh back up their win over Exeter Chiefs.
Seb Jewell comes into the side at full-back for his first start of the season, with Tom Arscott moving to the wing in place of Phil MacKenzie. The Canadian is named among the replacements.
The only other change to Welsh's matchday 23 sees back-row forward Alfie To'oala restored to the bench in place of Ed Williamson.
Among the other replacements is scrum-half Nick Runciman, who began his career at Gloucester before spending three seasons at London Welsh. He re-joined the Cherry and Whites in 2011 for a season before recently returning to the Exiles.
Welsh will gladly take a repeat of the last time the two sides met, at Kingsholm in a pre-season in August 2011. The Exiles came out on top, 24-23, thanks to tries from Mike Powell, Vili Ma'asi and a late effort from Rob Lewis, with Ross kicking the winning conversion.
It's more than fourteen years since London Welsh and Gloucester faced each other in a competitive match when Gloucester ran out 34-18 winners
Meanwhile, Gloucester director of rugby Nigel Davies keeps faith with the majority of the line-up that defeated Wasps, but does introduce three new faces. The only change to the backline sees Mike Tindall swap places with Henry Trinder to partner Billy Twelvetrees.
Up front, Australian Huia Edmonds is in for Darren Dawidiuk who picked up a knee injury against Wasps while number eight Ben Morgan is ruled out with a dead calf.
Finally, Peter Buxton, who has been in fine form in the Aviva Premiership A League, is named at blindside flanker with Sione Kalamafoni moving across to number eight.
It will be Gloucester's first clash with London Welsh in the Premiership at Kassam Stadium.
"It's very important that we've got the right mindset going into Sunday to play London Welsh," said Redpath.
"It's going to be a physical encounter. I think that the two sides that they've beaten probably didn't give them enough respect and, because of that, they finished on the wrong end of the result.
"They're a very strong team, a proud side. They've got a lot of points to prove, individually and collectively, and, if you get it wrong against them, they will beat you."
Form: London Welsh have now recorded successive Aviva Premiership victories over Exeter and Sale. The Exiles have won two of the three league games they have played at Kassam Stadium. Gloucester are unbeaten in their last three encounters since their opening day defeat at home to Northampton. Gloucester's most recent away loss was to London Irish at Madejski Stadium on 5 May. The two clubs have not clashed in competitive rugby since a 4th round tie in the Tetley's Bitter Cup at Old Deer Park on 3 January 1998 where Gloucester ran out 34-18 victors.
Rugby Union betting odds
London Welsh: 15 Seb Jewell, 14 Tom Arscott, 13 Sonny Parker, 12 Hudson Tonga'uiha, 11 Nick Scott, 10 Gordon Ross, 9 Tyson Keats, 8 Ed Jackson, 7 Michael Hills, 6 Daniel Browne, 5 Matt Corker, 4 Jonathan Mills (capt), 3 Paulica Ion, 2 Neil Briggs, 1 Frank Montanella.
Replacements: 16 Dan George, 17 Tom Bristow, 18 Arthur Joly, 19 Kirill Kulemin, Alfie To'oala, 21 Nick Runciman, 22 Ryan Davis, 23 Phil MacKenzie.
Gloucester: 15 Rob Cook, 14 Jonny May, 13 Mike Tindall, 12 Billy Twelvetrees, 11 James Simpson-Daniel, 10 Freddie Burns, 9 Dan Robson, 8 Sione Kalamafoni, 7 Andy Hazell, 6 Peter Buxton, 5 Jim Hamilton (capt), 4 Tom Savage, 3 Rupert Harden, 2 Huia Edmonds, 1 Nick Wood.
Replacements: 16 Koree Britton, 17 Dan Murphy, 18 Shaun Knight, 19 Will James, 20 Akapusi Qera, 21 Dave Lewis, 22 Henry Trinder, 23 Martyn Thomas.
Date: Sunday, September 30
Kick-off: 15:00 BST
Venue: Kassam Stadium
Referee: Llyr Apgeraint-Roberts
Assistant referees: Peter Huckle, Kevin Stewart
Timekeeper: Matthew Peters