Wasps will take on Bath at Adams Park in the Amlin Challenge Cup semi-finals after they overcame Gloucester 36-24.
The hosts were the better side in the weekend's European finale as fly-half Andy Goode helped steer Wasps past the Cherry and Whites.
Goode kicked 21 points on the night while tries that came from Matt Mullan, Carlo Festuccia and Will Helu helped Wasps on their way to victory.
Number eight Nathan Hughes was man-of-the-match however as his carrying ability was a major thorn in the side of Gloucester, especially during a half that saw Wasps go in at the break 13-3 up.
Gloucester did respond in the second-half with tries from Jonny May, Gareth Evans and Martyn Thomas, but Goode's boot kept them at bay as Wasps were deserved winners in the end.
Wasps will now face Bath in the semi-final stage of Europe's second tier competition on April 27.
Tries: Mullan, Festuccia, Helu
Con: Goode 3
Pen: Goode 4
Tries: May, Evans, Thomas
Con: Cook 3
London Wasps: 15 Andrea Masi, 14 Will Helu, 13 Elliot Daly, 12 Chris Bell (c), 11 James Short, 10 Andy Goode, 9 Joe Simpson, 8 Nathan Hughes, 7 James Haskell, 6 Sam Jones, 5 Kearnan Myall, 4 Joe Launchbury, 3 Jake Cooper-Woolley, 2 Carlo Festuccia, 1 Matt Mullan.
Replacements: 16 Tom Lindsay, 17 Simon McIntyre, 18 Phil Swainston, 19 Tom Palmer, 20 Guy Thompson, 21 Charlie Davies, 22 Joe Carlisle, 23 Charlie Hayter.
Gloucester: 15 Rob Cook, 14 Charlie Sharples, 13 Henry Trinder, 12 Billy Twelvetrees, 11 Jonny May, 10 Freddie Burns, 9 Jimmy Cowan, 8 Ben Morgan, 7 Matt Kvesic, 6 Sione Kalamafoni, 5 James Hudson, 4 Elliott Stooke, 3 Shaun Knight, 2 Dan George, 1 Nick Wood.
Replacements: 16 Huia Edmonds, 17 Yann Thomas, 18 Sila Puafisi, 19 Will James, 20 Gareth Evans, 21 Tavis Knoyle, 22 Thomas Young, 23 Martyn Thomas.
Referee: Pascal Gauzčre (France)
Assistant Referees: Marius Mitrea (Italy), Laurent Cardona (France)
TMO: Alan Falzone (Italy)