Leaders Clermont will be without a host of players when they return to Top 14 league action against Bayonne at Stade Jean-Dauger on Saturday.
With international call-ups and injuries, the domestic pace-setters could be without thirteen first-team players for the trip to the strugglers.
Thomas Domingo, Benjamin Kayser, Damien Chouly, Wesley Fofana and Jean-Marcellin Buttin are with France preparing for the Six Nations while Julien Bonnaire (arm), Daniel Kotze (ankle), Regan King (calf), Brock James (quadricep) and Gerhard Vosloo (hamstring) are all ruled out.
Davit Zirakashvili (calf) remains a doubt as does Julien Bardy, Nathan Hines and Thierry Lacrampe. Arthur Roulin is with France Sevens.