Western Province head coach Allister Coetzee fears the worst for hooker Tiaan Liebenberg after seeing the results of scans on his back.
Liebenberg missed last weekend's match against the Blue Bulls due to back spasms, but further scans have revealed damage to a spinal disc that could see the Springbok ruled out for the rest of the Currie Cup.
Captain Deon Fourie is also a more immediate absentee as he looks set to miss out against Griquas this weekend, as he recovers from a rib cage injury.
"More tests will be done [on Liebenberg] this week," said Coetzee.
"Usually with that kind of injury, the player needs a complete break from the game and I think he'll be sidelined for two or three months.
"I'm not sure how long Deon will still be out but he won't be available to play against Griquas.
In more positive news, Coetzee was pleased with his team's second-half showing against the Blue Bulls, as Province battled to a 29-18 victory despite being reduced to 14 men for 45 minutes after Michael Rhodes was shown a red card.
It means that Province remain unbeaten in this year's tournament after four wins and two draws, with Coetzee ruling out any talk of going through the competition without a loss as they defend their title.
"Our second-half performances this season have been a concern but against the Bulls we were far more clinical in the second half," added Coetzee.
"We've cut down on errors and that helped us a great deal, especially since we played with a man short.
"There has been a big improvement in our decision-making, especially in terms of the way we exited the Bulls' half, and we the result was that they opted to attack from positions deep inside their own half.
"We're not thinking about going through this competition unbeaten but rather thinking about winning the next match.
"We need to consolidate the things that are working are working well for us. We are scrumming well, even when we we're a man short against the Bulls.
"Our lineouts are not as good as they should be and that's just one of many other areas where we need to up our game."