Flying Bath winger Semesa Rokoduguni is poised to make his England Saxons debut against Scotland A at Scotstoun on Friday.
Rokoduguni starts out wide on the right wing in a back-three that includes Rob Miller - who impressed in the Saxons' loss to Ireland Wolfhounds on Saturday - and fellow new-cap Adam Thompstone.
Dan Robson of Gloucester also makes his Saxons bow at scrum-half, partnering troubled club-mate Freddie Burns at ten.
The side have lost their previous two clashes with their Scottish counterparts, including a 35-0 drubbing at Galashiles in 2012, so will be doubly keen to bounce back from their Wolfhounds disappointment with a victory on Friday.
"This group of young players worked hard in both preparing for and playing against an experienced Wolfhounds side at Kingsholm," said RFU Head of International Player Development Joe Lydon.
"We didn't deliver the win on Saturday but created some good opportunities and the team are building their knowledge of what is expected and our knowledge of them as a squad is also increasing. A further week together should help us continue to improve our collective understanding.
"We have an exciting young squad of real potential with new Saxons caps for Semesa Rokoduguni, Adam Thompstone and Dan Robson all of whom continue to play consistently well for their respective clubs.
"We are under no illusion how tough it will be for us in Glasgow against Scotland A, who've done well against us at this level in recent years, but our players have a lot of talent, endeavour and a willingness to work for each other to build on their club form.
"This squad has an average age of 24 and our aim is to continue working with them in an evolving long-term programme that compliments the excellent work done at their clubs in developing players capable of achieving success at club and at senior international level at the World Cups in 2015, 2019 and beyond."
15 Rob Miller, 14 Semesa Rokoduguni, 13 Elliot Daly, 12 Kyle Eastmond, 11 Adam Thompstone, 10 Freddie Burns, 9 Dan Robson, 8 Sam Dickinson, 7 Luke Wallace, 6 Calum Clark (c), 5 George Kruis, 4 Elliot Stooke, 3 Scott Wilson, 2 Dave Ward, 1 Alex Waller
Replacements: 16 Jamie George, 17 Nathan Catt, 18 Kieran Brookes, 19 Charlie Matthews, 20 Dave Ewers, 21 Joe Simpson, 22 Henry Slade, 23 Charlie Sharples