Biarritz took revenge for their shock defeat to Aironi last week with an emphatic 34-3 victory at Parc des Sports Aguilera in the Heineken Cup on Friday.
Tries from Argentine centre Marcelo Bosch, American wing Takudzwa Ngwenya, hooker Benoit August and a penalty try ensured that Biarritz secured the bonus point that keeps them firmly at the top of Pool Four.
The French club, runners-up in the competition last year, suffered a surprise 28-27 defeat to the Italian side at the Stadio Luigi Zaffanella six days ago to open up the pool.
But a repeat never looked on the cards as a 10th-minute try from Bosch and a penalty try 12 minutes later - both converted by France scrum-half Dimitri Yachvili, who also kicked two penalties - saw the hosts storm into a 20-0 half-time lead.
Ngwenya and August crossed for tries after the interval, with Yachvili adding the extras, before Aironi fly-half Riccardo Bocchino at least got his team on the scoresheet with a penalty on the hour.
Biarritz will now travel to Ulster in January looking to seal a home quarter-final.
Tries: Bosch, Penalty try, Ngwenya, August
Cons: Yachvili 4
Pens: Yachvili 2
Biarritz: 15 Dane Haylett-Petty, 14 Takudzwa Ngwenya, 13 Marcelo Bosch, 12 Damien Traille, 11 Iain Balshaw, 10 Julien Peyrelongue, 9 Dimitri Yachvili, 8 Imanol Harinordoquy, 7 Samiu Vahafolau, 6 Magnus Lund, 5 Erik Lund, 4 Jérôme Thion, 3 Campbell Johnstone, 2 Benoit August, 1 Yvan Watremez.
Replacements: 16 Romain Terrain, 17 Eusebio Guinazu, 18 Sylvain Marconnet, 19 Pelu Taele, 20 Wenceslas Lauret, 21 Ilikena Bolakoro, 22 Laurent Tranier, 23 Arnaud Mignardi.
Aironi: 15 Julien Laharrague, 14 Giiulio Toniolatti, 13 Matteo Pratichetti, 12 Gabriel Pizarro, 11 Giulio Rubini, 10 Riccardo Bocchino, 9 Pablo Canavosio, 8 Jaco Erasmus, 7 Simone Favaro, 6 Vickus Liebenberg, 5 Quintin Geldenhuys, 4 Marco Bortolami, 3 Fabio Staibano, 2 Luigi Ferraro, 1 Salvatore Perugini.
Replacements: 16 Roberto Santamaria, 17 Leo Gamboa, 18 Matias Aguero, 19 Josh Sole, 20 Gareth Krause, 21 Mickey Wilson, 22 James Marshall, 23 Giovanbattista Venditti.
Venue: Parc des Sports Aguilera
Referee: Andrew Small (England)
Assistant referees: Martin Fox (England), Alan Biggs (England)