Rhys Ruddock will lead the Irish Wolfhounds in Saturday's clash against the England Saxons at Kingsholm.
There is also a welcome return for hooker Richardt Strauss who has been named on the replacements bench. The squad announced Irish Wolfhounds head coach Anthony Foley contains some exciting combinations right across the selection.
The front row sees Munster, Ulster and Leinster combine in the shape of David Kilcoyne, Rob Herring and Martin Moore. The engine room is an all-Ulster affair with Iain Henderson and Dan Tuohy named in the second row.
Ruddock, Tommy O'Donnell and Robin Copeland form an all-action back row unit, while Leinster's Isaac Boss and Ian Madigan pair up at half-back.
Darren Cave and Robbie Henshaw will join forces in an exciting centre partnership with the back-three made up of Craig Gilroy, Fergus McFadden and Felix Jones.
The Wolfhounds can count on a strong bench which includes Jack McGrath, Stephen Archer, Robbie Diack, Jordi Murphy, Kieran Marmion and Ian Keatley as well as two players who have recently returned from long injury lay-offs - Strauss and Simon Zebo.
Irish Wolfhounds: 15 Felix Jones, 14 Fergus McFadden, 13 Robbie Henshaw, 12 Darren Cave, 11 Craig Gilroy, 10 Ian Madigan, 9 Isaac Boss, 8 Robin Copeland, 7 Tommy O'Donnell, 6 Rhys Ruddock (c), 5 Dan Tuohy, 4 Iain Henderson, 3 Martin Moore, 2 Rob Herring, 1 David Kilcoyne.
Replacements: 16 Richardt Strauss, 17 Jack McGrath, 18 Stephen Archer, 19 Robbie Diack, 20 Jordi Murphy, 21 Kieran Marmion, 22 Ian Keatley, 23 Simon Zebo.
Date: Saturday, January 25
Venue: Kingsholm, Gloucester
Kickoff: 17:00 GMTReferee: Ian Davies (Wales)
Assistant Referees: Wayne Davies (Wales), Jon Mason (Wales)
TMO: Gareth Simmonds (Wales)