London Wasps made it four wins from four in the Amlin Challenge Cup Pool stages as they overcame Grenoble 32-12 at Adams Park on Sunday.
The victory leaves the English side three points clear of Bayonne, who sit second in the group.
Wasps' tries came from flank James Haskell and left wing Tom Varndell while Ratu Alipate Ratini replied with a brace for the Top 14 outfit.
But it was the boot of home fly-half Joe Carlisle which proved the difference as he kicked 19 points to go with three from full-back Elliott Daly.
Tries: Haskell, Varndell
Con: Carlisle 2
Pen: Carlisle 5, Daly
Tries: Ratini 2
London Wasps: 15 Elliott Daly, 14 William Helu, 13 Ben Jacobs, 12 Charlie Hayter, 11 Tom Varndell, 10 Joe Carlisle, 9 Jack Winter-Moates, 8 Ed Jackson, 7 Sam Jones, 6 James Haskell (c), 5 Tom Palmer, 4 James Cannon, 3 Jake Cooper-Woolley, 2 Tom Lindsay, 1 Matt Mullan.
Replacements: 16 Carlo Festuccia, 17 Taione Vea, 18 William Taylor, 19 Esteban Lozada, 20 Rory Pitman, 21 Thomas Bell, 22 Andrew Suniula, 23 Josh Bassett.
Grenoble: 15 Matthieu Nicolas, 14 Ratu Alipate Ratini 13 Shane O'Leary, 12 Geoffroy Messina, 11 Florian Ninard, 10 Olly Barkley, 9 Nicolas Bézy, 8 Florian Faure (c), 7 Henri Vanderglas, 6 Cedric Beal, 5 Hendrik Roodt, 4 Alten Hulme, 3 Richard Choirat, 2 Anthony Hegarty, 1 Gregory Fabro.
Replacements: 16 Vincent Campo, 17 Romain David, 18 Dayna Edwards, 19 Thibault Rey, 20 Mathieu Loree, 21 Daniel Kilioni, 22 Rida Jaouher, 23 Roland Bernard.
Referee: Andrew McMenemy (Scotland)
Assistant Referees: Peter Allan (Scotland), Adrian Graves (Scotland)