The Waratahs are buoyed by the return of Wallaby duo Will Skelton and Tatafu Polota-Nau for Saturday's regular-season clash with the Reds.
Skelton returns from suspension and replaces Mitchell Chapman in the second-row for the derby fixture as the 'Tahs look to seal the Australian conference.
With the Brumbies hosting the Crusaders earlier on Saturday, the Waratahs will know what needs to be done as the pair currently sit level on 47. One significant boost to the side from Sydney however is the fact they have won one more game than the Canberra franchise going into this final round of the campaign.
In other team news for Michael Cheika's side, Hugo Roach drops down to the bench due to hooker Polota-Nau's return as Dave Porecki falls out of the 23.
Waratahs: 15 Israel Folau, 14 Taqele Naiyaravoro, 13 Adam Ashley-Cooper, 12 Kurtley Beale, 11 Matt Carraro, 10 Bernard Foley, 9 Nick Phipps, 8 Wycliff Palu, 7 Michael Hooper, 6 Jacques Potgieter, 5 David Dennis (c), 4 Will Skelton, 3 Sekope Kepu, 2 Tatafu Polota-Nau, 1 Benn Robinson.
Replacements: 16 Hugh Roach, 17 Jeremy Tilse, 18 Paddy Ryan, 19 Mitchell Chapman, 20 Dean Mumm, 21 Stephen Hoiles, 22 Brendan McKibbin, 23 Peter Betham.
Date: Saturday, 13 June
Venue: Allianz Stadium, Sydney
Kick-off: 19:40 local (09:40 GMT, 21:40 NZST, 11:40 SAST)
Referee: Nick Briant
Assistant referees: Matt O'Brien, Michael Hogan
TMO: Ian Smith