Pablo Lemoine has named the Uruguay team to face England in the final Pool A match at Manchester City Stadium on Saturday.
Lemoine has made two changes to the starting line-up that lost 47-15 to Fiji on Tuesday. Felipe Berchesi replaces Alejo Durán at fly-half and Mateo Sanguinetti steps in for Alejo Corral at loosehead prop.
Two is the second fewest changes Uruguay have made between successive RWC matches. Los Teros made only one change in 1999 to the side that had beaten Spain and faced Scotland.
Agustín Ormaechea has been cleared to play against England following his red card (resulting from two yellows) against Fiji.
Ormaechea's was the first dismissal at RWC 2015 and the first by a Uruguay player in a World Cup match.
Alejo Corral will make his 50th test appearance for Uruguay should he come on as a replacement.
Manuel Blengio is the only player in Uruguay's squad who has not yet played at Rugby World Cup 2015. He will make his World Cup debut if he comes off the bench.%u200B
Uruguay: 15 Gaston Mieres, 14 Santiago Gibernau, 13 Joaquin Prada, 12 Andres Vilaseca, 11 Rodrigo Silva, 10 Felipe Berchesi, 9 Agustín Ormaechea, 8 Alejandro Nieto, 7 Matias Beer, 6 Juan Manuel Gaminara, 5 Jorge Zerbino, 4 Santiago Vilaseca (c), 3 Mario Sagario, 2 Carlos Arboleya, 1 Mateo Sanguinetti
Replacements: 16 Nicolas Klappenbach, 17 Oscar Duran, 18 Alejo Corral, 19 Mathias Palomeque, 20 Diego Magnol 21 Agustín Alonso, 22 Alejo Durán, 23 Manuel Blengio
Date: Saturday, October 10
Venue: Manchester City Stadium, Manchester
Kick-off: 20:00 local (19:00 GMT)
Referee: Chris Pollock (New Zealand)
Assistant Referees: Angus Gardner (Australia), Federico Anselmi (Argentina)
TMO: George Ayoub (Australia)