The European Rugby Champions Cup will kick off in style when Leicester host Stade Français in a mouth-watering Round 1 fixture at Welford Road.
The Pool 4 meeting of the two-time winners and the reigning Top 14 champions is just one of a number of heavyweight confrontations scheduled for the opening weekend of Europe's elite club tournament on November 13-15 of this year.
Toulon, who completed an historic hat-trick of titles last season, begin their defence when they take on Bath at Stade Félix Mayol in the ultra-competitive Pool 5 on Sunday, November 15.
In Pool 1, Premiership champions, Saracens, host Toulouse in another huge Anglo-French game on the Saturday.
First-time PRO12 champions, Glasgow Warriors, have a tough task on their hands when they travel to Racing 92 in Pool 3 also on Saturday, November 14.
On that Saturday, Champions Cup debutants, Oyonnax, will play their first game in Europe's top flight at Stade Charles Mathon where Ulster will provide the opposition.
The December back-to-back fixtures in Rounds 3 and 4 which traditionally guarantee sell-out attendances across the pools have also thrown up some fascinating clashes with Toulon and Leinster renewing their rivalry. The venue for the Round 3 game between the three-time champions on Sunday, December 13 is yet to be confirmed, but the return will go ahead at Dublin's Aviva Stadium on Saturday, December 19.
The clashes of Munster and Leicester Tigers, Racing 92 and Northampton Saints, Ulster and Toulouse, as well as Wasps v Bath will also feature prominently in the key back-to-back series.
The dates and kick-off times for the Round 5 and 6 fixtures in both the Champions Cup and the Challenge Cup will be announced following the completion of the Round 4 games.
Round 1: 12/13/14/15 November
Round 2: 19/20/21/22 November
Round 3: 10/11/12/13 December
Round 4: 17/18/19/20 December
Round 5: 14/15/16/17 January 2016
Round 6: 21/22/23/24 January 2016
Quarter-finals: 7/8/9/10 April 2016
Semi-finals: 22/23/24 April 2016
Lyon 2016 finals
Challenge Cup – Friday, 13 May 2016; Grand Stade de Lyon (21.00)
Champions Cup – Saturday, 14 May 2016; Grand Stade de Lyon (17.45)