It is that time of the week when we put our heads on the chopping block with Planet Rugby's predictions.
Two massive semi-finals await this weekend in the Champions Cup where Saracens and Wasps face off in an all-English affair in Reading on Saturday before Leicester Tigers take on Racing 92 in Nottingam on Sunday.
Elsewhere, Harlequins host Grenoble in their Challenge Cup semi-final at Twickenham Stoop on Friday and in Saturday's play-off, Montpellier are at home against the Dragons at the Altrad Stadium.
On Saturday, Bath and Sale Sharks do battle at the Recreation Ground in the Premiership and there's several Super Rugby clashes in the Southern Hemisphere on Saturday and Sunday.
Paddy Power is our chosen bookie for our rugby bets so without further ado, let's get stuck in to our picks.
Saracens v Wasps
There's little to choose between these sides so placing a bet on Saracens to win by one point is a worth a bet at 22/1 while Wasps are at 25/1 for that same feat.
Although this is expected to be a closely fought battle, Wasps beat Sarries by more than 40 points when these teams last met, in the Premiership in February, so a Wasps win by between eight and 14 points looks worth a flutter at 7/1.
Billy Vunipola to score the opening try also looks solid at 14/1 as is Charles Piutau, who is at the same odds to also do that.
Leicester Tigers v Racing 92
This should be another tight contest and although Leicester are playing on English soil, in Dan Carter Racing have one of the game's best ever matchwinners.
A draw after 80 minutes, should be be a good option at 20/1 while Brice Dulin to score the opening try is worth a flutter at 5/1, as is Manu Tuilagi to be the last tryscorer at 14/1.
Harlequins v Grenoble
With Harlequins at home, they head into this match as favourites and placing a bet on their prolific finisher Tim Visser to score the first try is worth a flutter at 7/1.
Grenoble are an unpredictable side and, if you're brave, you can place a bet on them winning by between one and five points which is at 17/2.
Montpellier v Dragons
The Dragons are overwhelming underdogs but will use their quarter-final victory over last season's champions, Gloucester, as inspiration in this encounter.
If you're bold enough, then a Dragons triumph by between one and five points looks enticing at 13/1 while livewire scrum-half Sarel Pretorius is also a handy option at 4/1 to score a try during the 80 minutes.
With Demetri Catrakilis at fly-half for the home side, a Montpellier drop-goal as the first score of the game is also worth a bet at 33/1 as is Benjamin Fall to score the opening try which is at 11/1 odds.
Bath v Sale Sharks
These sides faced each other as recently as last weekend with Sale claiming a 29-17 at the AJ Bell Stadium. They have also beaten their hosts at the Rec in two of their last four visits.
Bath have battled this season so,Sale to win by between six and 10 points looks worth it at 6/1 while Will Addison is a handy bet at 11/1 to score the opening try.
Brumbies v Crusaders
The Crusaders head to Canberra on the back of a six-match winning streak and face their hosts, who are looking for their first triumph over the seven-time champions in seven years.
We're backing the Brumbies to clinch the win at 5/1 by between one and five points in their own backyard.
Other Super Rugby scores:
Sunwolves v Jaguares – Jaguares by 6
Hurricanes v Chiefs – Hurricanes by 3
Western Force v Waratahs – Waratahs by 8
Stormers v Reds – Stormers by 7
Kings v Lions – Lions by 20