Wing Charlie Sharples has been ruled out of Gloucester's season due to injury sustained in their 23-18 loss to London Irish two weeks ago.
The Cherry and Whites wing damaged the posterior cruciate ligaments in his knee.
He won't however be requiring surgery of any form, but he joins a growing list of wingers – Jonny May and Henry Purdy also out due to injury – on the sidelines.
Director of rugby David Humphreys remains optimistic despite having to go into the next few weeks without having a lot of options out wide.
"Charlie Sharples suffered a knee injury last week which will rule him out for the season and that adds him to the list of outside backs unavailable," Humphreys told the Gloucester Citizen.
"We are stretched but we have five big weeks ahead.
"He has been outstanding for the last two years for us, his level of performance, the consistency, his ability in the kick chase and to finish tries.
"He gives us huge momentum and is a huge loss along side Jonny and Henry but the positive is Tom Marshall and Henry Trinder coming back in."
Regardless of the growing list of backline injuries for Humphreys, he has lauded Tom Marshall for his efforts each week. The former Chiefs and Crusaders' back arrived Kingsholm this season.
"Tom Marshall will be an outstanding player in this competition, he will be an outstanding player for Gloucester," he added.
"That was just his second game since July and he didn't put a foot wrong.
"He dealt with the ball in the air but we want to give him the ball in space and areas of the pitch where he can do damage."