Bordeaux-Bègles scrum-half Baptiste Serin and Racing 92 flanker Bernard le Roux have been called up to train with France this week.
Serin replaces Morgan Parra, who is unable to train after suffering an ankle injury in Clermont's defeat on Sunday to Serin's UBB.
Le Roux meanwhile takes the place of Clermont lock Sébastien Vahaamahina who was also injured in Sunday's game.
The Racing back-row however will be unavailable for France's opening match of the Six Nations against Italy on February 6 because of his wedding.
New France head coach Guy Novès had already called up Marvin O'Connor on Sunday to replace the injured Benjamin Fall.