Scotland backs coach Jason O'Halloran believes the national side have enough depth to cover for Mark Bennett.
Bennett is an injury worry for Scotland heading into the Six Nations as he works his way back from a shoulder injury suffered in the Champions Cup against Racing 92.
Peter Horne is another concern with a foot injury, but O'Halloran feels that even if Bennett and Horne prove to be unavailable to face England, Scotland have enough options to remain a threat.
"[Bennett is] a day-to-day proposition at the moment. He is doing some jogging and, based on how he comes out of that, we will graduate his training," O'Hallaron said.
"He is a possibility to play but the medics will make that call next week.
"If you look at Peter Horne, Mark Bennett, Duncan Taylor, Matt Scott, there is some depth there now.
"So that's really comforting for me, we have four quality centres right there that we can choose from.
"I'm sure with a bit of work from the medical team we will go into the England game with a really good midfield."