Sale Sharks director of rugby Steve Diamond admitted that his side's decision-making buckled under pressure in their loss to Gloucester.
Nev Edwards scored two tries, the first provided by an excellent assist from Danny Cipriani, but despite the narrow scoreline in the second half the Sharks fell short.
Sale have now lost their last eight away games in all competitions dating back to February.
Friday's defeat keeps Sale in seventh place before the rest of the weekend's Premiership matches.
"We are disappointed and frustrated," Diamond said.
"It's always a difficult place to come but it was in the balance right the way through, the lead changed hands a couple of times.
"On the night we could not convert under pressure, we gave the ball away three or four times in their 22 and Gloucester didn't do that and that was the difference between the two sides.
"The missing ingredient at the moment is dealing with the pressure, we do the basics right but then we make simple knock-ons and we need to eradicate that from our game and we will be a good side."